DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13248 and CAT5

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_181041.1	Gene:	CAT5 / 818060	AraportID:	AT2G34960	Length:	569	Species:	Arabidopsis thaliana

Alignment Length:	619	Identity:	186/619 - (30%)
Similarity:	290/619 - (46%)	Gaps:	123/619 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RHILSGICTKM-NRTKSVPTD---------VMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTV 64
            |..||..|::. ||..|...|         ..|..:.|||..:|:...|.|.::||||:||||..
plant    29 RAALSQTCSRFKNRLVSRSDDENERFELKKQSEHEMKRCLTWWDLVWFGFGSVIGAGIFVLTGQE 93

  Fly    65 AKEMAGPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHM 129
            |.|.|||.|:||::::|..:||:..||.||...:|.||.::.|..|.:|:|.||:...|||||.:
plant    94 AHEQAGPAIVLSYVVSGLSAMLSVFCYTEFAVEIPVAGGSFAYLRIELGDFAAFITAGNILLESI 158

  Fly   130 LGAASVARAWSGYVDSMLGGWIGNTT-------LELTGGIHEPGLAQYPDVLAFLVCIVYAAALA 187
            :|.|:|||||:.|..::|     |.:       .:|:.|.:      ..|.:|.:|....|...:
plant   159 VGTAAVARAWTSYFATLL-----NRSPNALRIKTDLSSGFN------LLDPIAVVVIAASATIAS 212

  Fly   188 GGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNWSEAEGGFLPYGVGGVIAGAATCFYAFVG 252
            ...:.|::.|.:.:.:|..|:..||..||.:||..|.:.    |||:|..||...||..::|:.|
plant   213 ISTRKTSLLNWIASAINTLVIFFVIIAGFIHADTSNLTP----FLPFGPEGVFRAAAVVYFAYGG 273

  Fly   253 FDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLS 317
            ||||||..||.||||..||:..:.|:.::||.|.|::.:|::|...::|:|.|:...||..:.:.
plant   274 FDSIATMAEETKNPSRDIPIGLLGSMSIITVIYCLMALSLSMMQKYTDIDPNAAYSVAFQSVGMK 338

  Fly   318 WAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPL-LNLVVSGVMSA 381
            |.|||:::|||.||||.||.......|.:..:|...::...|..::|.|..|: .||:|: :.||
plant   339 WGKYLVALGALKGMTTVLLVGALGQARYVTHIARTHMIPPIFALVHPKTGTPINANLLVA-IPSA 402

  Fly   382 CLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRY---RPMERIHTTIRVPAVAGSPDDDDDDDE 443
            .:|....|..|...:||.||..:|::..::::.||   :...|:|.
plant   403 LIAFFSGLDVLASLLSISTLFIFTMMPIALLVRRYYVRQDTPRVHL------------------- 448

  Fly   444 DVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIFLSFAICVELK 508
                                                        :..:..:||:.:|   .:...
plant   449 --------------------------------------------IKLITCLLFVVVS---SMGTS 466

  Fly   509 VSWTQLYTGTW---------WALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGI 564
            ..|.....|:|         |.|...|.:.|          |..|.| ..::.|||||::|.|.|
plant   467 AYWGMQRKGSWIGYTVTVPFWFLGTLGIVFF----------VPQQRT-PKVWGVPLVPWLPCLSI 520

  Fly   565 FCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGI 598
            ..||.||..|.|:.:|||.|.....::.|||.|:
plant   521 ATNIFLMGSLGAMAFVRFGVCTLAMLLYYFLLGL 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	178/587 (30%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	22/48 (46%)
CAT5	NP_181041.1	2A0303	54..559	CDD:273330	178/594 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.870