DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13248 and slc7a5

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001121830.1	Gene:	slc7a5 / 797250	ZFINID:	ZDB-GENE-080818-4	Length:	523	Species:	Danio rerio

Alignment Length:	435	Identity:	107/435 - (24%)
Similarity:	181/435 - (41%)	Gaps:	63/435 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PTDVMET-PLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGI-ILSFILAGFISMLAAL 89
            |.|..|| .|.|.:...:...:.:|.::|:||:|....|.||....|: ::.:.:.|..|.:.||
Zfish    53 PADGEETVVLKRTITLVNGVAIIVGTIIGSGIFVTPTGVVKEAGSVGLSLVVWTVCGVFSTIGAL 117

  Fly    90 CYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNT 154
            ||||.||.:.|:|..|.|.....|...||:..|..||        :.|..|.|:.:.:
Zfish   118 CYAELGTTITKSGGDYAYILEVYGSLPAFLKLWIELL--------IIRPSSQYIVAYV------- 167

  Fly   155 TLELTGGIHEP--GLAQYPDVLAFLV---CIVYAAAL-AGGVKATAVFNSLLTLVNIAVMVLVIS 213
               ....|.:|  .:...|:..|.||   ||:...|: ...|||............:..:.|:|.
Zfish   168 ---FATYILKPIFPVCPVPETGAKLVACLCILLLTAVNCYSVKAATRVQDAFAAAKLLALGLIII 229

  Fly   214 VGFWYADGKNWSEAEGGFLPYGVGGVI--------AGAATCF-----------YAFVGFDSIATS 259
            :               ||:..|.|..:        .|:.|.|           :|:.|::.:...
Zfish   230 I---------------GFVEIGKGDTVELLPENSFKGSNTDFGNIGLALYSGLFAYGGWNYLNFV 279

  Fly   260 GEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLIS 324
            .||...|..::|.|.:|||.:|||.|:|.:.|....:...::..:.::...||..:|....::|.
Zfish   280 TEEMIEPYKNLPRAIIISLPIVTVVYVLTNLAYFTTLSPEKMLSSEAVAVDFGNYHLGPMAWIIP 344

  Fly   325 IGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDL 389
            :........::.||||...|..:..:.:|.|.|....|:|....||.:|:.:.:|:...|...|:
Zfish   345 VFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSLLSMIHPDLLTPLPSLIFTCIMTLLYAFSNDI 409

  Fly   390 AKLVEFMSIGTLLAYTIVSASVIILRYR--PMER-IHTTIRVPAV 431
            ..::.|.|....|...:....::.|||:  .:|| |...|.:|.|
Zfish   410 FSVINFFSFFNWLCIAMAIVGMMWLRYKKPELERPIKVNILLPIV 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	105/430 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
slc7a5	NP_001121830.1	2A0308	36..522	CDD:273332	107/435 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920