Protein Alignment CG13248 and slc7a4

DIOPT Version :10

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_919408.2
• Gene: slc7a4 / 796100
• ZFINID: ZDB-GENE-030919-2
• Length: 677
• Species: Danio rerio
• Alignment Length: 667
• Identity: 290/667 - (43%)
• Similarity: 410/667 - (61%)
• Gaps: 62/667 - (9%)

  Fly    17 CTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAG 81
            |.|:||.|::..|||.|.|.|||||.|:||||:|.|||:|:|||||||||:.|||.:::||::||
Zfish    15 CQKLNRLKTLDDDVMATSLKRCLNTVDLALLGVGGMVGSGLYVLTGTVAKDTAGPAVVISFLIAG 79

  Fly    82 FISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSM 146
            ..|::|||||||||.||||.||||::||:|:||.|||:||||::||:|:|.|:||||||||:||:
Zfish    80 VASLMAALCYAEFGARVPKTGSAYMFTYVSVGEIWAFLIGWNVILEYMIGGAAVARAWSGYLDSI 144

  Fly   147 LGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLV 211
            ....|.|.|.........|.||.|||:||..:.:|.:..::.||:.::..|.:.:.:::.|:|.:
Zfish   145 FNHRIQNFTESHVMRWEVPFLAHYPDLLAAAILLVASFFISFGVRVSSWLNHIFSAISMVVIVFI 209

  Fly   212 ISVGFWYADGKNWSEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVI 276
            :..||..||..|||..||||.|:|:.|::||.|||||||||||.||.|.|||.||..:||.||.|
Zfish   210 LVFGFILADPVNWSAREGGFAPFGLSGIMAGTATCFYAFVGFDVIAASSEEASNPQRAIPAATAI 274

  Fly   277 SLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFA 341
            ||.:....|:|||..||||:|...::|.::|.:||.:...|||.:::::|::|.|.|.||.:||:
Zfish   275 SLGLAATAYVLVSTVLTLMVPWHTLDPNSALSDAFFRRGYSWAGFIVAVGSICAMNTVLLSNLFS 339

  Fly   342 LPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTI 406
            |||.:||||.|||.||.|.::||.|:||::.::|.|.:.|.|||:|||..||:|:|||||||||.
Zfish   340 LPRIVYAMAEDGLFFSVFSRVNPVTKVPVIAILVFGSLMAILALIFDLEALVQFLSIGTLLAYTF 404

  Fly   407 VSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSSPTSE------------ 459
            |:||||:||::|.:...::    ...|...|.........|...||.|...:|
Zfish   405 VAASVIVLRFQPDKSSGSS----GAGGVKTDASSTPSGNQSGQQMDLSVAANEAQTFAQDGGELK 465

  Fly   460 ----------MIEEVLAGR-------LKAQFRCLEPLLGRF----EPGSVVSVAVMLFIFLSFAI 503
                      ::|...||:       |||::   ||.|||.    |||.||:.:|:..:....::
Zfish   466 EYESFSDKLQLVERQKAGKEKRAPGMLKARW---EPYLGRLLGDCEPGEVVAFSVLALMVSGVSL 527

  Fly   504 CVELKVSWTQLYTGTW---WALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIF 565
            ...|.....||:...|   ..|:|:..:...:   :|:|:||.|......|:||||||:|...|.
Zfish   528 SAVLVFGNNQLHLPVWSFTLLLVIFSVVFLLS---LALISVHEQRPNLKTFQVPLVPFIPGFSIL 589

  Fly   566 CNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEG-------EVCSSYSILMTTSEAGKVP 623
            .|:.||:.|..:||:||.|||..|::|||.|||.:||||       :|.:.|.:|         |
Zfish   590 LNVFLMLKLSPLTWIRFTVWVAAGLLVYFGYGIWHSKEGLREQQGQDVAARYVVL---------P 645

  Fly   624 WGSFKATSGGKKSSKHS 640
            .||...|....:...|:
Zfish   646 SGSLVETVQNVQPEGHT 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	271/606 (45%)
slc7a4	NP_919408.2	2A0303	11..627	CDD:273330	279/621 (45%)