DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and slc7a7

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001032648.1	Gene:	slc7a7 / 641560	ZFINID:	ZDB-GENE-051127-5	Length:	501	Species:	Danio rerio

Alignment Length:	396	Identity:	96/396 - (24%)
Similarity:	171/396 - (43%)	Gaps:	38/396 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DIALLG-----IGHMVGAGIYVLTGTVAKEMAGPGI-ILSFILAGFISMLAALCYAEFGTRVPKA 101
            :|:||.     :|:|:|:||:|....|.......|: ::.:.:.|..|:..||||||.||.:.|:
Zfish    35 EISLLNGVCLIVGNMIGSGIFVSPKGVLMYSGSYGLSLVVWTIGGIFSVFGALCYAELGTTITKS 99

  Fly   102 GSAYVYTYISMGEFWAFVIGW-NILLEHMLGAASVARAWSGYV-----DSMLGGWIGNTTLELTG 160
            |::|.|...:.|.|.||:..| ::|:......|.:|..:|.|:     .:.:..::.|..|
Zfish   100 GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAVIAITFSNYMVQPIFPTCIAPYVANRLL---- 160

  Fly   161 GIHEPGLAQYPDVLAFLVCI---VYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGK 222
                         .|..:|:   |..|.:..|.:....|    |.|.:..::.||..|.......
Zfish   161 -------------AAACICLLTFVNCAYVKYGTRVQDFF----TYVKVVALIAVIITGLVKIFQG 208

  Fly   223 NWSEAEGGF--LPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGY 285
            .....||.|  ..:..|.|.....:..:::.|:|::....||.|||..::|:|..||:.:|||.|
Zfish   209 YTQNFEGLFSDSSHDPGDVALALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIAISMPIVTVIY 273

  Fly   286 ILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMA 350
            ||.:.|...::||..|..:.::...|......:..:.|.:.........|..|:.|..|..:..:
Zfish   274 ILTNLAYYTILPIPAILDSDAVAVTFADQVFGYLNWTIPVAVAFSCFGGLNASIVAASRLFFVGS 338

  Fly   351 SDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILR 415
            .:|.|......|:.|...|:..|:.:|.|:.....|.|:.||:.:.|........:.....:.||
Zfish   339 REGHLPDYLCMIHITRFTPIPALLFNGAMALVYLCVEDVFKLINYYSFSYWFFVGLSILGQLYLR 403

  Fly   416 YRPMER 421
            ::..:|
Zfish   404 WKQPDR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	96/396 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
slc7a7	NP_001032648.1	2A0308	2..492	CDD:273332	96/396 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920