Protein Alignment CG13248 and slc7a1a

DIOPT Version :10

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_021327949.1
• Gene: slc7a1a / 559627
• ZFINID: ZDB-GENE-091116-69
• Length: 651
• Species: Danio rerio
• Alignment Length: 631
• Identity: 255/631 - (40%)
• Similarity: 373/631 - (59%)
• Gaps: 79/631 - (12%)

  Fly    22 RTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISML 86
            |.|.|..:..|:.|:|||||||:..||:|..:|||:|||.|.||:|.|||.|:|||::|...|:|
Zfish    15 RVKVVNCNSEESRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVLSFLIAALASVL 79

  Fly    87 AALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWI 151
            |.|||||||.||||.||||:|:|:::||.|||:.|||::|.:::|.:|||||||...|.::|..|
Zfish    80 AGLCYAEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSATFDELIGKHI 144

  Fly   152 GNTTLELTGGIHEPG-LAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVG 215
            .:...:.. .::.|| ||:|||:.:..:.:.....||.|||.:|:.|.:.|.:||.|::.::..|
Zfish   145 EHFCRQYM-SMNAPGVLAEYPDMFSVFIILTLTGLLAFGVKESAMVNKVFTCINILVLLFMVVSG 208

  Fly   216 FWYADGKNW----------------------SE---AEGGFLPYGVGGVIAGAATCFYAFVGFDS 255
            ......|||                      ||   .:|||:|:|..||::|||||||||||||.
Zfish   209 LVKGTLKNWHLDPDEILNATNSTLNATQPLPSEEMLGQGGFMPFGFTGVLSGAATCFYAFVGFDC 273

  Fly   256 IATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAK 320
            |||:|||.|||..:||:..|.||.:..|.|..||||||:|:|...::..:.||.||..:....|.
Zfish   274 IATTGEEVKNPQRAIPIGIVSSLLICFVAYFGVSAALTMMMPYYMLDKNSPLPVAFKYVGWEGAT 338

  Fly   321 YLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLAL 385
            |.:::|:||.::|:|||::|.:||.::|||.|||||.....|:..|:.|:...::||.::|.:|.
Zfish   339 YAVAVGSLCALSTSLLGAMFPMPRVLWAMADDGLLFKFMAGISERTKTPIKATIMSGFLAAIMAF 403

  Fly   386 VFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDDEDVASQSS 450
            :|||..||:.||||||||||:|:|.|::|||:| |:...|..   :|.:.:|
Zfish   404 LFDLKDLVDLMSIGTLLAYTLVAACVLVLRYQP-EQFSQTYH---IANTHED------------- 451

  Fly   451 MDTSSPTSEMIEEVLAGRLKAQF---RCLEPLLGRFEP----GSVVSVAVML--FIFLSFAICVE 506
            |:.|...|.....:|.| ::.:|   ..|.|.:  .||    |..|::...|  .:.|||::
Zfish   452 MEMSETISTPSMGILPG-VEERFSFKNLLFPDI--IEPSNLSGFTVNICTSLLGLLILSFSL--- 510

  Fly   507 LKV-----SWTQLYTGTWWALIIYGFIIFAAGTCVAVIAV---HNQNTRGLIFKVPLVPFVPALG 563
            |.|     ||.          ||...::|  |.||.|..:   ..::...|.||||.:||:|.:.
Zfish   511 LAVRGGIASWN----------IITLAVLF--GLCVIVTFIIWRQPESKTKLSFKVPCLPFIPVVS 563

  Fly   564 IFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEGEVCSS 609
            :|.|:.||:.||..||:||.:|:.||:|:||.|||.:|.|..:..|
Zfish   564 MFVNVYLMMQLDRGTWIRFAIWMSIGLVIYFGYGIWHSTEAALAHS 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	250/613 (41%)
slc7a1a	XP_021327949.1	2A0303	4..603	CDD:273330	253/623 (41%)