DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and Slc7a10

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_059090.3	Gene:	Slc7a10 / 53896	MGIID:	1858261	Length:	530	Species:	Mus musculus

Alignment Length:	406	Identity:	99/406 - (24%)
Similarity:	173/406 - (42%)	Gaps:	59/406 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 IGHMVGAGIYVLTGTVAKEMAGPGIIL-SFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISM 112
            ||:::|:||::....|.:.....|:.| .::|.|.::.|.:|||||.|..:||:|..|.|.....
Mouse    56 IGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIF 120

  Fly   113 GEFWAFVIGWN-ILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAF 176
            |....|::.|: :|:.:....|.::..:|.||                   .:|         .|
Mouse   121 GGLAGFLLLWSAVLIMYPTSLAVISMTFSNYV-------------------LQP---------VF 157

  Fly   177 LVCIVYAAALAGGVKATAVFNSLLTLVN------------------IAVMVLVISVGFWYADGKN 223
            ..||  ..|.|..|.:.|.. .|||.||                  :..:.|:|:|||......:
Mouse   158 PNCI--PPATASRVLSMACL-MLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGH 219

  Fly   224 WSE-----AEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTV 283
            :.|     |...::...||.:........:||.|::.:....||..:|..::|.|..||:.:||.
Mouse   220 FEELRPTNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTF 284

  Fly   284 GYILVSAA-LTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMY 347
            .|...:.| .|.|.| .|:..:.::...||:..|.:..:::.:.........:.|.||...|..:
Mouse   285 VYTFTNVAYFTAMSP-QELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTSSRLCF 348

  Fly   348 AMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVI 412
            :.|.:|.|.|....|:.....|:..|:|....:|.:.||.|...|:.::|....|.|.:....::
Mouse   349 SGAREGHLPSFLAMIHVRRCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLL 413

  Fly   413 ILRYRPMERIHTTIRV 428
            :||:| ...:|..|:|
Mouse   414 VLRWR-RPALHRPIKV 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	99/406 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
Slc7a10	NP_059090.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
		2A0308	38..503	CDD:273332	99/406 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	508..530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850