Protein Alignment CG13248 and slc7a2

DIOPT Version :9

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001008584.1
• Gene: slc7a2 / 494041
• ZFINID: ZDB-GENE-041212-5
• Length: 640
• Species: Danio rerio
• Alignment Length: 631
• Identity: 256/631 - (40%)
• Similarity: 373/631 - (59%)
• Gaps: 62/631 - (9%)

  Fly     8 ILRHILSGICTKMNRTKSVPTDVM-ETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGP 71
            :|.|.|: ....:.|.|:|....: |:.|.|||:|.|:..||:|..:|||:|||.|.|||..:||
Zfish     1 MLEHCLT-FGRSLVRRKNVDQGCLEESKLCRCLSTVDLIALGVGSTLGAGVYVLAGEVAKGSSGP 64

  Fly    72 GIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVA 136
            .|::||::|...|::|.|||||||.||||.||||:|:|:::||.|||:.|||::|.:::|.:|||
Zfish    65 SIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVA 129

  Fly   137 RAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLT 201
            |||||..|.::||.| ....::...:..||||:|||..|..:.::.:..|:.|||.:|..|.:.|
Zfish   130 RAWSGTFDEIIGGHI-EKFCKMYFKMSLPGLAEYPDFFAVCLILLLSGLLSFGVKESAWVNKIFT 193

  Fly   202 LVNIAVMVLVISVGFWYADGKNWSEAE-------------------------GGFLPYGVGGVIA 241
            .||:.|::.||..||...|..||:.:|                         |||.|||.||.:|
Zfish   194 AVNVLVLMFVIISGFVKGDSLNWNISEESLVNITVVKRNISSAANVTSDYGAGGFFPYGFGGTLA 258

  Fly   242 GAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAAS 306
            |||||||||||||.|||:|||.|||..:||:..|:||.|..:.|..||||||||:|...::..:.
Zfish   259 GAATCFYAFVGFDCIATTGEEVKNPQRAIPIGIVVSLLVCFLAYFGVSAALTLMMPYYLLDEKSP 323

  Fly   307 LPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLL 371
            ||.||..:....|||:::.|:||.::|:||||:|.|||.::|||.||:||....|:: ..|.|:.
Zfish   324 LPLAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGVLFRFLSKLS-KRQSPVA 387

  Fly   372 NLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRP---MERIHTTIRVPAVAG 433
            ..:.:|..:|.:|.:|||..||:.|||||||||::|:|.|:||||:|   .||...:
Zfish   388 ATMAAGTTAAIMAFLFDLKALVDMMSIGTLLAYSLVAACVLILRYQPDASFERSRIS-------- 444

  Fly   434 SPDDDDDDDEDVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIF 498
                   :.::...:|.:..|.....|:::   |.:..:.....|||......|||:|:|::.:.
Zfish   445 -------EGKEEVGESELTESESHLNMLKD---GGVTLRSLLHPPLLPTENTSSVVNVSVIITVL 499

  Fly   499 LSFAICVELKVSWTQLYTG------TWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVP 557
            :   :||   ||....|.|      ..|||.:....:|....||.:|....|..:.:.|.|||:|
Zfish   500 V---VCV---VSTLNTYYGQAIIAMELWALGVLAASLFIFIICVFLICRQPQTRKKVSFMVPLLP 558

  Fly   558 FVPALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKE 603
            |:|.|.||.|:.|||.|...||:||.:|:.||.::||.||:.:|.|
Zfish   559 FLPILSIFVNVYLMVQLSGDTWIRFSIWMAIGFLIYFGYGMWHSDE 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	249/604 (41%)
		AA_permease_C	551..601	CDD:290617	26/49 (53%)
slc7a2	NP_001008584.1	2A0303	6..604	CDD:273330	253/624 (41%)
		AA_permease_C	552..602	CDD:290617	26/49 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593044
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.780