Protein Alignment CG13248 and slc7a3a

DIOPT Version :9

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001007330.2
• Gene: slc7a3a / 492363
• ZFINID: ZDB-GENE-041114-206
• Length: 644
• Species: Danio rerio
• Alignment Length: 647
• Identity: 258/647 - (39%)
• Similarity: 377/647 - (58%)
• Gaps: 87/647 - (13%)

  Fly     5 RRAILRHILSGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMA 69
            :.|...|||.       |.:::.....||...|||:|.|:..||:|..:|||:|||.|.||:|.|
Zfish     4 KMASFGHILL-------RRRALDFSGEETRFARCLSTLDLVALGVGSTLGAGVYVLAGEVAREKA 61

  Fly    70 GPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAAS 134
            ||.|:|.|::|...||||.|||||||.||||.||||:|:|:::||.|||:.|||::|.:::|.||
Zfish    62 GPAIVLCFLVAALSSMLAGLCYAEFGARVPKTGSAYLYSYVTVGEIWAFITGWNLILSYVIGTAS 126

  Fly   135 VARAWSGYVDSMLGGWIGN-----TTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATA 194
            ||||||...|:::...|.|     ..:::.|.:    ||:|||:.|.::.::....||.||..:|
Zfish   127 VARAWSSTFDNLIEQKISNFFRASMAMKVPGKV----LAEYPDLFALILILLLTGLLAFGVSESA 187

  Fly   195 VFNSLLTLVNIAVMVLVISVGFWYADGKNW-------------SEAE--------GGFLPYGVGG 238
            :.|.:.|.:|:.|:..:|..||...:..||             :|.|        |||.|:|:||
Zfish   188 LVNKIFTGINLIVLGFIIISGFVKGNTANWNLTYEYFINDTNITEPERIESTFGSGGFAPFGLGG 252

  Fly   239 VIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINP 303
            :::|||||||||||||.|||:.||||||..||||..|.||.:....|..||||||||:|..::|.
Zfish   253 ILSGAATCFYAFVGFDCIATTSEEAKNPMRSIPVGIVASLLICFFAYFGVSAALTLMMPYYKLNT 317

  Fly   304 AASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQV 368
            .:.|||||..:..:.|:|::::|:||.::|:||||:|.:||.:||||.|||||....::|..|:.
Zfish   318 QSPLPEAFSYVGWAPARYIVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRSLSRMNKRTKT 382

  Fly   369 PLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRP--------MERIHTT 425
            |||..:.||:::|.:|.:||||.||:.|||||||||::|:..|:||||:|        .|::...
Zfish   383 PLLATIASGIVAALMAFLFDLAALVDLMSIGTLLAYSLVAVCVLILRYQPGNLSSSSQTEKLVEL 447

  Fly   426 I--RVPAVAGSPDDDDDDDEDVASQSSMDTS---------SPTSEMIEEVLAGRLKAQFRCLEPL 479
            :  ...||.|...|:...:.|.:.:....|:         ||| ||...::.|..
Zfish   448 VGGEKVAVCGDSGDEYGVELDDSPRKEKFTAKLLLVPSKDSPT-EMSGTIVYGTT---------- 501

  Fly   480 LGRFEPGSVVSVAV-MLFIFLSFAI--CVELKVSWTQLYTGTWWALIIYGFIIFAAGTCVAVIAV 541
                   :::||.: :|.:.|:..:  .:.|::.|..       |.:|   ::.....||.||..
Zfish   502 -------AIISVLITVLCVVLAQRLESIINLEIVWVT-------ACVI---LVLLCVLCVIVIFR 549

  Fly   542 HNQNTRGLIFKVPLVPFVPALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKE 603
            ..::...|.|||||:|::|...||.||.||:.||..||.||.||:.||..:||.|||.:|.|
Zfish   550 QPESKEALTFKVPLLPWLPLFSIFVNIYLMMQLDVATWCRFTVWMAIGFAIYFGYGIWHSTE 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	252/618 (41%)
		AA_permease_C	551..601	CDD:290617	28/49 (57%)
slc7a3a	NP_001007330.2	2A0303	4..611	CDD:273330	257/645 (40%)
		AA_permease_C	559..609	CDD:290617	28/49 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750