DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and tadr

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_724308.2	Gene:	tadr / 35370	FlyBaseID:	FBgn0032911	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	719	Identity:	137/719 - (19%)
Similarity:	251/719 - (34%)	Gaps:	158/719 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DIALLGIGHMVGAGIYVLTGTVA-KEMAGPGIILSFILAGFISMLAALCYAEF-GTRVPKAGSAY 105
            |:...|.|..:..|..|::..:. .|.:.|.:::..:||.....:||.|.... ..::|...:..
  Fly     8 DVLCSGSGARLALGASVISYLIVYNEASAPSLLVGVVLATVYGAMAARCKTSLRSLQMPYVRATN 72

  Fly   106 VYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQY 170
            .:.:..:     |:..|...|..:...|::||..|..:|:|.||......|......:||    :
  Fly    73 KFDFSCL-----FLAIWLDALATVCACAALARTLSACLDAMTGGLARILILGRNAPANEP----W 128

  Fly   171 PDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNWSEAEGGFLPYG 235
            ||||...|..:.......|::.:..|:.:|||....:..::.:||:|..|...|| |:..|.|.|
  Fly   129 PDVLGVSVVFLVTGMFMLGLEHSRAFSLILTLGMFGLNAILSAVGWWRGDMLAWS-ADSYFQPDG 192

  Fly   236 VGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISE 300
            :..|..|.|...|:|.|.......|...        .||:|: .:|:...:|.:..|:.::....
  Fly   193 ISSVFLGTALLTYSFPGDWPQQLRGGRF--------TATLIT-GLVSTSLLLTAICLSTVVHYRS 248

  Fly   301 INPAASLP-------EAFGQLNLSWAKYLI--SIGALCGMTTTLLGSLFALPRCMYAMASDGLLF 356
            .....::|       ..|.:|..:.|..|:  |..|...:...|.|.:..|....:.:.|..:.:
  Fly   249 QEDYVAVPLFNILDENGFHKLVPASACMLLLTSSAAFLELFPELYGIVVRLATSEWRILSKQISY 313

  Fly   357 SCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRP--- 418
            ......|     |:|.:.::|.|.|.||....|..|...::.|.:....:.:..::.:.|||
  Fly   314 ESSESGN-----PVLAVFIAGSMCAMLAFACPLQHLSYTLAAGHMGGVFLRALYLLYIPYRPKYM 373

  Fly   419 ----------------------------------MERI--------HTTIRVPAVA--------- 432
                                              ::|.        |:.::.|...
  Fly   374 APSSESSLSYSRLSTAPFAKSSSYSSAATSSSSRLKRSLWKIGLPKHSNLKKPKTKPRNKQELEK 438

  Fly   433 ---------------------------GSPDDDDDDDEDVASQSSMDTSSPTSEMIEE------- 463
                                       |.|...|.:..|...:|..|||:....:::|
  Fly   439 EWLLLGEPTSPCPQREGRDVESTILSDGEPPPSDFEYPDKFDKSDSDTSTDIDAIVDEYREKIKV 503

  Fly   464 VLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIFLSFAICVE-LKVSWT-QLYTGTWWALII-- 524
            ..||.|:...|.  |.:..:.    |::..::.|.|..|:|:. |.:.|. ...||....||:
  Fly   504 TTAGPLERSVRV--PTVSSWR----VTIFAIVVIGLGIALCIAGLMMHWAPAALTGGIGVLIVTI 562

  Fly   525 -YGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIFCNILLMVHLDAVTWVRFFVWVCI 588
             .|||....|:.:.|                 .|.:..:.:...::|.......:|....:|:..
  Fly   563 MMGFIPKYTGSVINV-----------------SPVICGMSLLMGVILFSGCAIHSWPGLLIWLMA 610

  Fly   589 GMVVYFLYGIRNSKEGEVCSSYSILMTTSEAGKVPWGSFKATSGGKKSSKHSIFERFTGRSKPED 653
            |:::.    ||..|....|..::.:|   .|..:|..|.|:..|....|..::....|....|..
  Fly   611 GLILV----IRCDKYCCNCFEHTTIM---NAQLIPSVSGKSNMGSASGSASNLAGPSTSIRIPRP 668

  Fly   654 KKSI 657
            .|.:
  Fly   669 PKGM 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	125/663 (19%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	7/49 (14%)
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	52/210 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910