DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and Slc7a6

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_006531198.1	Gene:	Slc7a6 / 330836	MGIID:	2142598	Length:	532	Species:	Mus musculus

Alignment Length:	405	Identity:	100/405 - (24%)
Similarity:	186/405 - (45%)	Gaps:	52/405 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DIALLG-----IGHMVGAGIYVLTGTVAKEMAGPGI-ILSFILAGFISMLAALCYAEFGTRVPKA 101
            :|:||.     :|:|:|:||:|....|.|..|..|: ::.:.:.|..|::.||||||.||.:.|:
Mouse    61 EISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLSLIVWAIGGLFSVVGALCYAELGTTITKS 125

  Fly   102 GSAYVYTYISMGEFWAFVIGW-NILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEP 165
            |::|.|...:.|.|.||:..| ::|:......|.:|..::.|:            ::.:....:|
Mouse   126 GASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYI------------IKPSFPTCDP 178

  Fly   166 GLAQYPDVLAFLVCI---VYAAALAGG--VKATAVFNSLLTLVNIAVMVLV-ISVGF--WYAD-- 220
            .......:.|..||:   |..|.:..|  |:.|..:..:|.|:.|.:|.|| :..|.  .:.|
Mouse   179 PYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQGHTEHFQDAF 243

  Fly   221 -GKNWSEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVG 284
             |.:|:          ||.:.....:..:::.|:|::....||.|||..::|:|..||:.:||:.
Mouse   244 KGSSWN----------VGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLI 298

  Fly   285 YILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAM 349
            |||.:.|...::.|.:::.:.::...|.........:.|.|.........|..|:||..|..:..
Mouse   299 YILTNVAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVG 363

  Fly   350 ASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVI-- 412
            :.:|.|.:....|:.....|:..|:.:..|:....:|.|:..|:.:.|..   .:..|..||:
Mouse   364 SREGHLPNLLSMIHIERFTPVPALLFNCTMTLIYLVVKDVFLLINYFSFS---YWFFVGLSVVGQ 425

  Fly   413 -ILRY------RPME 420
             .||:      ||::
Mouse   426 LYLRWKEPDWPRPLK 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	100/405 (25%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
Slc7a6	XP_006531198.1	2A0308	34..518	CDD:273332	100/405 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920