Protein Alignment CG13248 and Slc7a4

DIOPT Version :10

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001100548.1
• Gene: Slc7a4 / 303787
• RGDID: 1305905
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 641
• Identity: 272/641 - (42%)
• Similarity: 400/641 - (62%)
• Gaps: 40/641 - (6%)

  Fly     1 MPSSRRAILRHILSGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVA 65
            :||:.|      |:..|.|:||.|.:.....||.|.|||:|.|:.|||:|.|||:|:||||||||
  Rat     5 LPSTAR------LARFCQKLNRLKPLEESSTETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVA 63

  Fly    66 KEMAGPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHML 130
            |:||||.::|||::|...|:||||||||||.|||:.||||::||:||||.|||:||||:|||:::
  Rat    64 KDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLI 128

  Fly   131 GAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAV 195
            |.|:||||||||:|::....|.|.|....|....|.||.|||.||..:.:|.:|.::.|.:.::.
  Rat   129 GGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLAHYPDFLAAGILLVASAFVSCGARVSSW 193

  Fly   196 FNSLLTLVNIAVMVLVISVGFWYADGKNWSEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSG 260
            .|...:.:::.|::.:|.:||..|...|||..||||.|:|..|::||.|||||||||||.||.|.
  Rat   194 LNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASS 258

  Fly   261 EEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISI 325
            ||||||..::|:|..|||.:....|||||..||||:|...::|.::|.:||.:....||.:::::
  Rat   259 EEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYGWAGFIVAV 323

  Fly   326 GALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLA 390
            |::|.|.|.||.:||:|||.:||||:|||.|..|.:::|.||||::.::|.||:.|.|||:.||.
  Rat   324 GSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLE 388

  Fly   391 KLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSS 455
            .||:|:|||||||||.|:.|:|:||::              ..||...........:....|:.|
  Rat   389 ALVQFLSIGTLLAYTFVATSIIVLRFQ--------------KASPPSSPCPASPGPTVKKYDSFS 439

  Fly   456 PTSEMIEEVLA-----GRLKAQFRCLEPLLGRFE---PGSVVSVAVMLFIFLSFAICVELKVSWT 512
            ...::::.|.|     |:|:.   .|:|.||..:   ||:.|:.|:.:.|..:.::...|....:
  Rat   440 DHIQLVDAVQASMSEPGQLRP---ALKPFLGFLDGLSPGTAVTWALGILIASAISLACVLVFGNS 501

  Fly   513 QLYTGTW---WALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIFCNILLMVHL 574
            .|:...|   ..|::.|.:..::   :.|:..|.|..:...|::||||..|||.|..|:.||:.|
  Rat   502 ALHLPRWGYVLLLVVSGAVFLSS---LLVLGAHQQQKKQDTFQIPLVPLTPALSILLNLCLMLKL 563

  Fly   575 DAVTWVRFFVWVCIGMVVYFLYGIRNSKEGEVCSSYSILMTTSEAGKVPWGSFKAT 630
            ..:||:||..|:.:|:||||.|||.:|||.:   ...:.:||:.....|.||.:.|
  Rat   564 SYLTWLRFIFWLLVGLVVYFGYGIWHSKENQ---REPLELTTAHYVVFPSGSLEET 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	255/581 (44%)
Slc7a4	NP_001100548.1	2A0303	14..592	CDD:273330	260/597 (44%)