DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and SPAPB24D3.02c

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_593989.1	Gene:	SPAPB24D3.02c / 2543419	PomBaseID:	SPAPB24D3.02c	Length:	543	Species:	Schizosaccharomyces pombe

Alignment Length:	530	Identity:	121/530 - (22%)
Similarity:	220/530 - (41%)	Gaps:	162/530 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 LTGTVAKEM---AGPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYT-YISMGEFWAFV- 119
            |.|::|..|   || |::.|:.:.....:..|...:|..:.:|.:||.|.:| |:|..::.||:
pombe    66 LVGSMAFSMNCGAG-GMVWSWFVGATCLLPIAFALSELASSMPTSGSLYFWTAYLSPPKYRAFLS 129

  Fly   120 --IGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLA--QYPDVLAFLVCI 180
              :|:.:.|.:..|.||...|.:|.|             :.|..:..|..|  :|.: ....|.:
pombe   130 WFLGYVLALAYSTGFASTIYAAAGLV-------------QATASVANPSYAPTKYEE-YGIYVAL 180

  Fly   181 VYA--AALAGGVKATAVFNSLLTLVNI-AVMVLVISV------------GFWYADGKNWSEAEGG 230
            .:|  |.:....|..|.|:|...:..| .:::.:||:            .:.:.:.:|:|    |
pombe   181 SFACSALIVLPTKFLARFSSFNVVFQICTILIFIISLAASSTSETRNTGSYIFGNFENYS----G 241

  Fly   231 FLPYGVGGVIAGAATCF----YAFVGFDSIATSGEEAKNPSVSIPVATVISLFV-VTVGY-ILVS 289
            :...|...::     ||    :...||:|.||..|||||.|.:.|:|.:.||.| :.:|: |:::
pombe   242 WTNMGWSFIL-----CFTTPVWVLSGFESCATIVEEAKNASKAAPIAIISSLTVSLFMGFCIMIT 301

  Fly   290 AALTLMIPISEINPAASLPEAFGQLNLSWAKY--LISIGALCGMTTTLLGSL--------FALPR 344
            .|.|:....|.|     |...:|: .:|...|  |...||: |::..|:.:|        .|..|
pombe   302 IAGTMGHDFSSI-----LNTPYGE-PVSQVLYNNLGKRGAV-GVSAVLIIALCFNCSALCLASSR 359

  Fly   345 CMYAMASD-GLLFS-CFGKIN----PTTQVPLLNL--VVSGVMS----ACLALVFDLAKLVEFMS 397
            .::|.|.| ||..| .|.|:.    |...:.|:||  ::.|::.    ..::.:|:||.:..|:|
pombe   360 EIFAFARDKGLPGSWIFRKLTPGGIPLNAILLVNLYTIIVGLLMLVNVTAISSIFNLAIIAFFIS 424

  Fly   398 IGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSSPTSEMIE 462
                  |::                      |.|.
pombe   425 ------YSL----------------------PLVC------------------------------ 431

  Fly   463 EVLAGRLK-AQFRCLEPLLGRF-EPGSVVSVA-----VMLFIFLSFAICVELKVSWTQLYTGTWW 520
            .:|..||. .:|.|     |:| :|.|:|:||     .::.:|.|:....:::::         |
pombe   432 RLLFNRLNPGKFYC-----GKFSKPISIVAVAWLWFMALMLLFPSYQNPNKVEMN---------W 482

  Fly   521 ALIIYGFIIF 530
            |:::.||.:|
pombe   483 AIVVLGFTVF 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	121/530 (23%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
SPAPB24D3.02c	NP_593989.1	2A0304	34..512	CDD:273331	121/530 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I2865
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030