DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and isp5

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_595000.1	Gene:	isp5 / 2543028	PomBaseID:	SPAC1039.09	Length:	580	Species:	Schizosaccharomyces pombe

Alignment Length:	428	Identity:	92/428 - (21%)
Similarity:	165/428 - (38%)	Gaps:	77/428 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISMLAALCY 91
            |.|.....|.|.|....|.::|||..:|.|::|.:....:|.....:::.:.|.|.:.::.....
pombe    71 PEDGKPQKLKRTLTARHIQMIGIGGAIGTGVWVGSKNTLREGGAASVLICYSLVGSMVLMTVYSL 135

  Fly    92 AEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHM------LGAASVARAWSGYVDSMLGGW 150
            .|.....|..||.:.|....:...|.|.:|||.|...:      |..||:.          |..|
pombe   136 GELAVAFPINGSFHTYGTRFIHPSWGFTLGWNYLASFLATYPLELITASIC----------LQFW 190

  Fly   151 IGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSL--LTLVNIAVMVLVIS 213
            |     .:..||       :..|...|:|.|....:.|..:.....:||  :.:|...:..:||.
pombe   191 I-----NINSGI-------WITVFIALLCFVNMFGVRGYGEVEFFVSSLKVMAMVGFIICGIVID 243

  Fly   214 VGFWYADGKNWSEA----EGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVAT 274
            .|....|.:.:..|    :..|: :|..|..:..:|..:::.|.:.|..:..|.|||:.:.|.|
pombe   244 CGGVRTDHRGYIGATIFRKNAFI-HGFHGFCSVFSTAAFSYAGTEYIGIAASETKNPAKAFPKA- 306

  Fly   275 VISLFV-VTVGYILVSAALTLMIP-----ISEINPAASLP--EAFGQLNLSWAKYLISIGALCGM 331
            |..:|: |::.|||....::|:|.     ::.::..|:.|  .|.....:....::::...|..:
pombe   307 VKQVFIRVSLFYILALFVVSLLISGRDERLTTLSATAASPFILALMDAKIRGLPHVLNAVILISV 371

  Fly   332 TTTLLGSLFALPRCMYAMASDG-------------------LLFSCFGKINPTTQVPLLNLVVSG 377
            .|...|..:...|.:::||..|                   ....|||.:....:
pombe   372 LTAANGITYTGSRTLHSMAEQGHAPKWFKYVDREGRPLLAMAFVLCFGALGYICE---------- 426

  Fly   378 VMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILR 415
              ||....|||.  |:...::.||..:..::.|.||.|
pombe   427 --SAQSDTVFDW--LLSISNLATLFVWLSINVSYIIYR 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	90/423 (21%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
isp5	NP_595000.1	LysP	37..579	CDD:223903	92/428 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I1891
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.960