DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and SPBPB2B2.01

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_596849.1	Gene:	SPBPB2B2.01 / 2541403	PomBaseID:	SPBPB2B2.01	Length:	585	Species:	Schizosaccharomyces pombe

Alignment Length:	453	Identity:	92/453 - (20%)
Similarity:	170/453 - (37%)	Gaps:	78/453 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSSRRAILRHILSGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVA 65
            :|:....:.|..::|...:.|:..|....     |.|.|.:..|.::|||..:|.|::|.:....
pombe    50 VPAKEENVFRRFINGFKIEKNQQDSAGQG-----LKRRLKSRHIQMIGIGGAIGTGVWVGSSKSL 109

  Fly    66 KEMAGPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHML 130
            .......:::.:.:.|.:.........|.....|..||...:....:.|.|.|.:.||
pombe   110 YRGGAASVLIDYCIVGTMVFCTVYALGELAVAFPTRGSFVTHATRFIDESWGFALSWN------- 167

  Fly   131 GAASVARAWSGYVDSMLGGWIGNTTLELTGGI----HEPGLAQYPDVLAFLVCIVYAAALAGGVK 191
                       ||.|    :|....||||.|.    :...|.....|..|:|.:.:....  |||
pombe   168 -----------YVFS----FIVTIPLELTTGTMMIKYWTNLNSGIWVTVFIVFLFFINIF--GVK 215

  Fly   192 ATAVFNSLLTLVNIAVMV------LVISVGFWYADGKNWSEA----EGGFLPYGVGGVIAGAATC 246
            .......:::.:.:..|.      ::|..|....|.:.:...    |..| .:...|..|...:.
pombe   216 GYGEMEFIMSTIKVVAMCGFIILGIIIDCGGVPTDHRGYMGTHIFRENAF-RHKFKGFCAVFTSA 279

  Fly   247 FYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINP-------- 303
            .::|.|.:.:..:..|.:||:.:.|||...:||.:.:.|||....::|:  ||..:|
pombe   280 AFSFSGTEYVGVAAAETENPAKAFPVAVRQTLFRIAIFYILSLFIVSLL--ISGADPRLTSYHGV 342

  Fly   304 -AASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQ 367
             |:....|....|:.....:::...|..:.::....|:|..|.::::..:|....||..::...:
pombe   343 DASPFVLAIKDANIKALPSILNAIILISVISSANAQLYAGSRAIHSLGCNGFAPKCFTLVDREGR 407

  Fly   368 VPLLNLVVSGVMSACLALVFDLAKLVE-------------FMSIGTLLAYTIVSASVIILRYR 417
             ||:.|::       |.|...|..|||             ...:|||..:.  |..:..:|||
pombe   408 -PLVALLI-------LFLFMFLGYLVETGQYDTVFDWMLSISGLGTLFCWG--SICLAHIRYR 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	87/422 (21%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
SPBPB2B2.01	NP_596849.1	LysP	36..584	CDD:223903	92/453 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I1891
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.960