DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and aat1

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_595053.1	Gene:	aat1 / 2541042	PomBaseID:	SPBC359.03c	Length:	579	Species:	Schizosaccharomyces pombe

Alignment Length:	489	Identity:	101/489 - (20%)
Similarity:	177/489 - (36%)	Gaps:	132/489 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISMLAALCYAEFGTRVP 99
            |.|.|:|..:.|:.||..:|:|:||.:|:...:.....:|:::||.|.:.........|.....|
pombe    73 LKRGLSTRHMQLMSIGGAIGSGLYVGSGSALADGGPASVIINYILIGIMMFFVIYALGEMAVAYP 137

  Fly   100 KAGSAYVYTYISMGEFWAFVIGWNILLEHML----GAASVARAWSGYVDSMLGGWIGNTTLELTG 160
            .|||...|....:...|.|.:.||....:.:    ...:.|..::.:.|.....||.
pombe   138 VAGSFNTYATRFIDPAWGFAVSWNYFFNYFVTFPFELTTCAITFTFWTDVNCAVWIS-------- 194

  Fly   161 GIHEPGLAQYPDVLAFLVCIV----YAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADG 221
                          .|||.::    :...:.|.|:.......::..|...::.::|:.|....|.
pombe   195 --------------IFLVVVIGINLFGVRVFGEVEFVLALIKVVATVGFIILAIIINCGGVPTDH 245

  Fly   222 KNWSEAEGGFL----PY--GVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFV 280
            :.:.   ||.:    |:  |..|..:...|..::|.|.:.:..:..|..:|..::|.|.....:.
pombe   246 RGYI---GGSIIKQKPFRHGFKGFCSVYTTAAFSFSGTEIVGLAAAEVGDPRKTLPGAVKQVFWR 307

  Fly   281 VTVGYILVSAALTLMI--------------------PISEINPAASLPEAFGQLNLSWAKYLISI 325
            |.:.||:....:.|:|                    .|.|.| ...||..|.      |..:||:
pombe   308 VAIFYIVSLILIGLLISPDDPKLMGNGSASVSPFVLAIQEAN-IKGLPSVFN------AVIIISV 365

  Fly   326 GALCGMTTTLLGSLFALPRCMYAMA-----------SDG-----------LLFSCFGKINPT--- 365
            .::...:|...|      |.::.||           :|.           |.|..|..||..
pombe   366 ISVTNSSTYTAG------RTLHGMANLKQAPAFFKYTDRLGRPLIAMIVVLSFGFFAYINEANNN 424

  Fly   366 ------TQVPLLNLVVSGVM------SACLA-LVFDLA--------KLVEFMS-IGTLLAYTIVS 408
                  |....| |.:||:.      |.||: ::|.||        |.:.|:| :|       :.
pombe   425 GNDISDTVFDWL-LAISGLSNFFTWGSICLSHIMFRLAFKKQGHSLKELGFVSPMG-------IW 481

  Fly   409 ASVIILRYR---PMERIHTTIRVPAVAGSPDDDD 439
            .|||.|.:.   .|...:.:: .| :.|||:.:|
pombe   482 GSVIGLGFNILCLMAEFYVSL-FP-IGGSPNAND 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	101/489 (21%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
aat1	NP_595053.1	LysP	28..578	CDD:223903	101/489 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	3	2.910