DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and meu22

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_596348.1	Gene:	meu22 / 2540779	PomBaseID:	SPBC19F8.06c	Length:	574	Species:	Schizosaccharomyces pombe

Alignment Length:	372	Identity:	78/372 - (20%)
Similarity:	145/372 - (38%)	Gaps:	72/372 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISMLAALCY 91
            |.|..:  |.|.|....:.::.||..||.|::|.:|....:.....|:::|.:.|...:......
pombe    52 PEDTQD--LQRKLKPRHMQMIAIGGCVGTGLFVGSGNALADGGPASILIAFAVIGTYVLFTTSAL 114

  Fly    92 AEFGTRVPKAGSAYVYTYISMGEFWAFVIG---W-----NILLEHMLGAASVARAW--SGYVDSM 146
            ||.....|.:||.|.|....:...|.|.:|   |     .:.|| :..|..:...|  ||.|..
pombe   115 AELSAIYPVSGSFYTYFSKFIDPAWGFAVGIQYWLSFAVTVPLE-LTVAPLIINFWNASGPVSI- 177

  Fly   147 LGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLV 211
               || :....:...|:..|...|.:|..||..:                 .:::::...::.::
pombe   178 ---WI-SVFYVIIIAINIWGTEGYGEVEFFLSIM-----------------KVISVIGFVILSII 221

  Fly   212 ISVGFWYADGKN------WSEA---EGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPS 267
            |:.|....|.:.      |.:.   ..||     .|:.|.:....::..|.:.:..:..|||||.
pombe   222 IAAGGVPTDDRGVIGVSYWKQPLVFNNGF-----KGLCAVSVIAIFSLSGTELVGLAASEAKNPQ 281

  Fly   268 VSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLP--EAFGQLNLSWAKYLISI----- 325
            .::|.|.....:.:.:.||:....|||::|       :.||  ......|:..:.::|:|
pombe   282 KTVPAAVKQIFWRIFLFYIVALFMLTLVVP-------SDLPGLRTSDNSNVLISPFVIAIQLANI 339

  Fly   326 -------GALCGMTTTLLG--SLFALPRCMYAMASDGLLFSCFGKIN 363
                   ..:..::|..:|  :.:|..|.::|:|.:|.....|.|.|
pombe   340 RALPSIMNVVILLSTLSVGNSASYAASRALFALAKNGYAPKIFNKTN 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	76/367 (21%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
meu22	NP_596348.1	LysP	17..544	CDD:223903	78/372 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	3	2.910