Protein Alignment CG13248 and Slc7a4

DIOPT Version :9

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001346821.1
• Gene: Slc7a4 / 224022
• MGIID: 2146512
• Length: 700
• Species: Mus musculus
• Alignment Length: 642
• Identity: 280/642 - (43%)
• Similarity: 404/642 - (62%)
• Gaps: 40/642 - (6%)

  Fly    13 LSGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSF 77
            |:..|.|:||.|.:....|||.|.|||:|.|:.|||:|.|||:|:|||||||||:||||.::|||
Mouse    76 LARFCQKLNRLKPLEESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSF 140

  Fly    78 ILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGY 142
            ::|...|:||||||||||.|||:.||||::||:||||.|||:||||:|||:::|.|:||||||||
Mouse   141 LVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGY 205

  Fly   143 VDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAV 207
            :|::....|.|.|....|....|.||.|||.||..:.:|.:|.::.|.:.::..|...:.:::.|
Mouse   206 LDAIFNHSIRNFTESHLGVWQVPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIV 270

  Fly   208 MVLVISVGFWYADGKNWSEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPV 272
            ::.:|.:||..|...|||..||||.|:|..|::||.|||||||||||.||.|.||||||..::|:
Mouse   271 ILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPM 335

  Fly   273 ATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLG 337
            |..|||.:....|||||..||||:|...::|.::|.:||.:...|||.:::::|::|.|.|.||.
Mouse   336 AIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLS 400

  Fly   338 SLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLL 402
            :||:|||.:||||:|||.|..|.:::|.||||::.::|.||:.|.|||:.||..||:|:||||||
Mouse   401 NLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLL 465

  Fly   403 AYTIVSASVIILRYRPMERIHTTIRVPAVAGSP-------DDDDDDDEDV-ASQSSMDTSSPTSE 459
            |||.|:.|:|:||::......:    |.:| ||       |...|..:.| |.|:||  |.|
Mouse   466 AYTFVATSIIVLRFQKASPPSS----PCLA-SPGPTAKKYDSFSDHIQLVGAEQTSM--SEP--- 520

  Fly   460 MIEEVLAGRLKAQFRCLEPLLGRFE---PGSVVSVAVMLFIFLSFAICVELKVSWTQLYTGTW-- 519
                   |:|:.   .|:|.||..:   ||:.|:.|:.:.:..:.::...|....:.|:...|
Mouse   521 -------GQLRP---ALKPFLGFLDGCSPGTAVAWALGILVASAISLACVLVFGNSDLHLPQWGY 575

  Fly   520 -WALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIFCNILLMVHLDAVTWVRFF 583
             ..|:|.|.:..::   :.|:..|.|..:...|::||||..|||.|..|..||:.|..:||:||.
Mouse   576 VLLLVISGAVFLSS---LLVLGAHQQQKKQDTFQIPLVPLTPALSILLNTCLMLKLSYLTWLRFI 637

  Fly   584 VWVCIGMVVYFLYGIRNSKEGEVCSSYSILMTTSEAGKVPWGSFKATSGGKKSSKHS 640
            .|:.:|:||||.|||.:|||.:   ...:.:||:.....|.||.:.|....:.|..|
Mouse   638 FWLLVGLVVYFGYGIWHSKENQ---REPLELTTAHYVVFPSGSLEETVQAVQPSSQS 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	263/584 (45%)
		AA_permease_C	551..601	CDD:290617	26/49 (53%)
Slc7a4	NP_001346821.1	AA_permease_2	79..657	CDD:330980	269/600 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	419	1.000	Domainoid score	I644
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20883
Inparanoid	1	1.050	511	1.000	Inparanoid score	I1301
Isobase	1	0.950	-	0	Normalized mean entropy	S2810
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		oto93012
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	LDO	PTHR43243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.810