DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13248 and Slc7a5

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_035534.2	Gene:	Slc7a5 / 20539	MGIID:	1298205	Length:	512	Species:	Mus musculus

Alignment Length:	423	Identity:	100/423 - (23%)
Similarity:	183/423 - (43%)	Gaps:	56/423 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGI-ILSFILAGFISMLAALCYAEFGTRV 98
            |.|.:...:...:.:|.::|:||:|....|.||...||: ::.:.:.|..|::.||||||.||.:
Mouse    47 LQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLSLVVWAVCGVFSIVGALCYAELGTTI 111

  Fly    99 PKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIH 163
            .|:|..|.|.....|...||:..|..||        :.|..|.|:.:::
Mouse   112 SKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQYIVALV---------------- 152

  Fly   164 EPGLAQY-----------PDVLAFLV---CIVYAAAL-AGGVKATAVFNSLLTLVNIAVMVLVIS 213
               .|.|           |:..|.||   |::...|: ...|||............:..:.|:|.
Mouse   153 ---FATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIIL 214

  Fly   214 VGFWYADGKNWSEAEGGFLP---------YGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVS 269
            :|| ...||:..:.:...|.         ..||.::....:..:|:.|::.:....||..||..:
Mouse   215 LGF-IQMGKDMGQGDASNLQQKLSFEGTNLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRN 278

  Fly   270 IPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTT 334
            :|:|.:|||.:||:.|:|.:.|....:..:::..:.::...||..:|....::|.:........:
Mouse   279 LPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGS 343

  Fly   335 LLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIG 399
            :.||||...|..:..:.:|.|.|....|:|....|:.:||.:.:|:...|...|:..::.|.|..
Mouse   344 VNGSLFTSSRLFFVGSREGHLPSVLSMIHPQLLTPVPSLVFTCIMTLMYAFSRDIFSIINFFSFF 408

  Fly   400 TLLAYTIVSASVIILRYR--PMER-IHTTIRVP 429
            ..|...:....::.||::  .:|| |...:.:|
Mouse   409 NWLCVALAIIGMMWLRFKKPELERPIKVNLALP 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	100/423 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
Slc7a5	NP_035534.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
Slc7a5	NP_035534.2	2A0308	35..511	CDD:273332	100/423 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010