DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and aat-9

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001021788.1	Gene:	aat-9 / 190250	WormBaseID:	WBGene00000010	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	431	Identity:	105/431 - (24%)
Similarity:	192/431 - (44%)	Gaps:	39/431 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 MNRTKSVPT--DVMET----PLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFI 78
            |:..:.:||  ||..|    .|..|::..      |.:::||||::..|||.|.....|:.|...
Worm     1 MSSIEDLPTVGDVAATRHQMGLWSCMSYV------IANIIGAGIFITPGTVLKLALTNGMALVVW 59

  Fly    79 L-AGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGW-NILLEHMLGAASVARAWSG 141
            | .|.||::..:||.|.||.:...|..:.|......|..||...| .:::.....||..|:.:..
Worm    60 LGCGLISLIGGICYIELGTSIRDPGCDFAYNVYVGWEGIAFSFMWVGVIMSFPASAAVQAQTFGQ 124

  Fly   142 YVDSMLGG-WIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNI 205
            |:.:.|.. |...:..::   |.|.||. :..::...|..:||..     |..:.|...:|:..:
Worm   125 YIVAGLSPIWHLGSPYDV---ILERGLG-FALIIILTVLNLYAID-----KYASKFQIFVTIAKL 180

  Fly   206 AVMVLVISVGFWYADGKNWSE-AEGGFLP-----YGVGGVIAGAATCFYAFVGFDSIATSGEEAK 264
            ..:.::|..||||...|..:| .:..|.|     |.:|.:........::|.|:|.:.....|.|
Worm   181 LSLAIIIVTGFWYLIVKGETEHFKDAFTPLPNEKYDIGQISLAFYGALWSFAGWDILNYGTPEIK 245

  Fly   265 NPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNL---SWA-KYLISI 325
            ||..::|:|.:..:..||:.|:.::.:...::....:..::::...|.::.|   |:| .::|||
Worm   246 NPRRTMPIALLGGISAVTLVYMAMNVSYMTVLDTETLKNSSAVAADFARITLGDFSYAIPFMISI 310

  Fly   326 GALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLA 390
             .|.|   ||..::|...|..:|.|.:|.|.:....||..:..|...|:...:.:..:..| |..
Worm   311 -LLIG---TLNSNIFCGSRFTHAAAREGHLPTFLSCINAESNSPRAALLFQLICTIAVTFV-DTE 370

  Fly   391 KLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAV 431
            .|:.:::...........|:::.:|||.:......||||.:
Worm   371 SLITYVTFVMFGQRVFTMAALLWIRYRNIPVHPDAIRVPLI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	100/417 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
aat-9	NP_001021788.1	2A0308	19..477	CDD:273332	99/413 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920