Protein Alignment CG13248 and C50D2.2

DIOPT Version :9

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_493662.1
• Gene: C50D2.2 / 183650
• WormBaseID: WBGene00016806
• Length: 589
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 297/638 - (46%)
• Similarity: 403/638 - (63%)
• Gaps: 89/638 - (13%)

  Fly    14 SGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFI 78
            |.:..::.|.|::|...:.|||.|||:||||.|||:|||:|||||||||:|.:..|||.|||||:
 Worm     4 SALRERVFRLKNLPAGEIATPLRRCLSTFDITLLGVGHMIGAGIYVLTGSVVRNTAGPSIILSFL 68

  Fly    79 LAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYV 143
            ||||.|:|:||||||||.|.|||||||.|||:.:||.|||||||||:||||||||:|||:||||:
 Worm    69 LAGFASLLSALCYAEFGARFPKAGSAYTYTYVGVGELWAFVIGWNIILEHMLGAAAVARSWSGYL 133

  Fly   144 DSMLGGWIGNTTLELTGGIHEPG--LAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIA 206
            ||:||..|.|:|:..||.:||..  ...|||:||||:.::.|..:|.|.|.:..|||.||::||.
 Worm   134 DSLLGNVISNSTIARTGHLHEASSFFGDYPDLLAFLLIVLVAFFVALGSKVSTNFNSFLTILNIG 198

  Fly   207 VMVLVISVGFWYADGKNWS----EAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPS 267
            ::|:|:..|..:||...||    :....|.||||.|:.||||:||:|::|||.:||:|||||:|:
 Worm   199 IVVIVVFYGITFADFSLWSGVDEKGNSRFFPYGVSGMFAGAASCFFAYIGFDGLATAGEEAKDPA 263

  Fly   268 VSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMT 332
            .|||:||..|:.:||:.|:|:||:||||||.:.::|.|:..:||......:|.|.:|:|||.|||
 Worm   264 RSIPIATFSSMTIVTLSYVLMSASLTLMIPYNMVHPTAAFSDAFTMRGAEFASYAVSVGALFGMT 328

  Fly   333 TTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMS 397
            |:|:|.:||||||:::||.||||||....:||.||||...|::.|.::|.:||:||:..||||:|
 Worm   329 TSLVGGMFALPRCVFSMADDGLLFSSLASVNPKTQVPTQALLIFGFLTAIIALLFDITTLVEFLS 393

  Fly   398 IGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSSPTSEMIE 462
            |||||||:||||.||:|||:|             |.:.|:...|:
 Worm   394 IGTLLAYSIVSACVIVLRYQP-------------AYNVDEGQFDN-------------------- 425

  Fly   463 EVLAGRLKAQFRCLEPLLG---RFEPG-SV-----VSVAVMLFIFLSFA--------ICVELKVS 510
               .|:|:...    |..|   :.:|| |:     |.:|.|.|..|.|:        :|
 Worm   426 ---GGKLRFSI----PFCGFLDKLQPGHSIYYGMSVMIASMFFSGLGFSSGYLYGTVLC------ 477

  Fly   511 WTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIFCNILLMVHLD 575
              |::.....||||..|:.         |..|..|...|.|||||||.:|||.:..|.|:||||.
 Worm   478 --QIFLLVNIALIILSFLF---------ICAHYPNNTPLDFKVPLVPLIPALSLLINTLMMVHLA 531

  Fly   576 AVTWVRFFVWVCIGMVVYFLYGIRNSKEGEV--------CSSYSILMTTSEAG 620
            .:||:|..||:.||.|:||.|||.:||| ||        .|:|..:::...||
 Worm   532 WITWLRLVVWMSIGFVIYFGYGIHHSKE-EVQDAEKFSKSSTYESVVSGVVAG 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	285/593 (48%)
		AA_permease_C	551..601	CDD:290617	29/49 (59%)
C50D2.2	NP_493662.1	2A0303	6..559	CDD:273330	288/609 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161276
Domainoid	1	1.000	463	1.000	Domainoid score	I228
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	544	1.000	Inparanoid score	I630
Isobase	1	0.950	-	0	Normalized mean entropy	S2810
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D290636at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		otm14275
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	LDO	PTHR43243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750