DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and aat-1

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_501707.1	Gene:	aat-1 / 177793	WormBaseID:	WBGene00000002	Length:	493	Species:	Caenorhabditis elegans

Alignment Length:	420	Identity:	101/420 - (24%)
Similarity:	188/420 - (44%)	Gaps:	52/420 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGI-ILSFILAGFISMLAALCYAEFGTRV 98
            |.:.|..|:...:.:|.::|:||:|....|.::....|: ::.::::|..:.:.|.||||.||.:
Worm    28 LEKSLTLFNGVSMIVGCIIGSGIFVSPTGVQEQAGSVGLSLIVWLISGIFTAIGAYCYAELGTLI 92

  Fly    99 PKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIH 163
            .|:|..|.|...:.|.|.||:                 |.|   :::::......|.:.||..|:
Worm    93 KKSGGDYAYIMEAFGPFVAFI-----------------RLW---IEAIVVRPCTVTIVALTFAIY 137

  Fly   164 EPGLAQY------PDV----LAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVG--- 215
              ||..:      |||    ||.|:.::..|.....|:...:.....|:..:..:.|:|..|
Worm   138 --GLRPFFPDCAPPDVVAELLAILLIVLMTAINCISVRLATIVQDWFTIAKVVALCLIILTGLGL 200

  Fly   216 FWYADGKNWSEAEGGFLPYGVGGVIAGAATCFY----AFVGFDSIATSGEEAKNPSVSIPVATVI 276
            .::.:.:.....|..|  ..........:..||    |:.|::.:....||.:||..::|:|..|
Worm   201 LFFGESQYKDSFENIF--ENTSQDFTKVSLAFYSGLFAYSGWNFLNFIVEELQNPKRNLPLAIAI 263

  Fly   277 SLFVVTVGYILVSAALTLMIPISEI--NPAASLPEAFGQLNLSWAK--YLISIGALCGMTTTLLG 337
            |:...||.|:|.:.||...|...|:  :||.::..|    |..:.|  :::.:...|....:..|
Worm   264 SITSCTVIYVLTNVALYTAISPDEMLESPAVAVLFA----NKLYGKFAFIMPLCVACSTIGSANG 324

  Fly   338 SLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMS-ACLALVFDLAKLVEFMSIGTL 401
            .:|...|..|:.|.:|.:.:....||..|:.|:..::::|.:| |.|....|:.:|:.::.|...
Worm   325 VIFTSARLFYSGAREGQMPAVLTMINKKTKTPIPAVILTGALSIAYLLASKDVYQLINYIQISYW 389

  Fly   402 LAYTIVSASVIILRYRPMERIHTTIRVPAV 431
            ||.....|::..|| |.|......|:||.:
Worm   390 LAIGTAIAALFWLR-RTMPDASRPIKVPLI 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	101/420 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
aat-1	NP_501707.1	2A0308	2..491	CDD:273332	101/420 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920