DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and SLC7A13

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_620172.2	Gene:	SLC7A13 / 157724	HGNCID:	23092	Length:	470	Species:	Homo sapiens

Alignment Length:	416	Identity:	99/416 - (23%)
Similarity:	168/416 - (40%)	Gaps:	101/416 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 HMVGAGIYVL-TGTVAKEMAGPGIILSFILAG--FISMLAALCYAEFGTRVPKAGSAYVYTYISM 112
            :::||||:|. .|.:|......|:.|. :.||  .::|.:.||.||.....|.:|:.|.:.....
Human    25 NIIGAGIFVSPKGVLAYSCMNVGVSLC-VWAGCAILAMTSTLCSAEISISFPCSGAQYYFLKRYF 88

  Fly   113 GEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQY------- 170
            |...||:..|..|   .||:..||               |...|          ||:|
Human    89 GSTVAFLNLWTSL---FLGSGVVA---------------GQALL----------LAEYSIQPFFP 125

  Fly   171 ----PDV----LAFLVCIVYAAALAGGVK-------ATAVFN-SLLTLVNIAVMVLVISVGFWYA 219
                |.:    ||..:..:.....:.|||       |::|.. |:|:.:::..:|.:|.
Human   126 SCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIR------ 184

  Fly   220 DGK--------NWSEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVI 276
             ||        |..:||...:.:.:..:..|    ::|:.|.........|.|.|..:||.....
Human   185 -GKKENVERFQNAFDAELPDISHLIQAIFQG----YFAYSGGACFTLIAGELKKPRTTIPKCIFT 244

  Fly   277 SLFVVTVGYILVSAA-LTLMIPISEINPAASLPEAFGQLNLSWA-------KYLISIGALCGMTT 333
            :|.:|||.|:||:.: ||::.|...::..|        :.::||       .:::.......:.:
Human   245 ALPLVTVVYLLVNISYLTVLTPREILSSDA--------VAITWADRAFPSLAWIMPFAISTSLFS 301

  Fly   334 TLLGSLFALPRCMYAMASDGLLFSCFGKIN----PTTQVPLLNLVVSGVMSACLALVFDLAKLVE 394
            .||.|:|...|.:|..:.:|.|...|..:|    |.|.|  |.||..|.::..|..:.||...:.
Human   302 NLLISIFKSSRPIYLASQEGQLPLLFNTLNSHSSPFTAV--LLLVTLGSLAIILTSLIDLINYIF 364

  Fly   395 FMSIGTLLAYTIVSASVIILRYRPME 420
            |  .|:|.:..::   :.|||.|..|
Human   365 F--TGSLWSILLM---IGILRRRYQE 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	99/416 (24%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
SLC7A13	NP_620172.2	AA_permease_2	16..398	CDD:290254	99/416 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157286
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840