Protein Alignment CG13248 and Slc7a2

DIOPT Version :10

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_006509313.1
• Gene: Slc7a2 / 11988
• MGIID: 99828
• Length: 720
• Species: Mus musculus
• Alignment Length: 633
• Identity: 260/633 - (41%)
• Similarity: 364/633 - (57%)
• Gaps: 89/633 - (14%)

  Fly    22 RTKSVPTDVME-TPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISM 85
            |.|.|..|.:| :.|.|||.|.|:..||:|..:|||:|||.|.|||..:||.|::||::|...|:
Mouse    78 RRKIVTLDSLEDSKLCRCLTTVDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASV 142

  Fly    86 LAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGW 150
            :|.|||||||.||||.||||:|||:::||.|||:.|||::|.:::|.:||||||||..|.:|...
Mouse   143 MAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQ 207

  Fly   151 IG---NTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVI 212
            ||   .|..::    :..|||:|||..|..:.::.|..|:.|||.:|..|...|.:||.|::.|:
Mouse   208 IGQFFKTYFKM----NYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVM 268

  Fly   213 SVGFWYADGKNWSEAE------------------------GGFLPYGVGGVIAGAATCFYAFVGF 253
            ..||...:..||..:|                        |||:|||..|.:|||||||||||||
Mouse   269 VAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGF 333

  Fly   254 DSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSW 318
            |.|||:|||.:||..:||:..|.||.|..:.|..||||||||:|...::..:.||.||..:..|.
Mouse   334 DCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVRWSP 398

  Fly   319 AKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACL 383
            |||::|.|:||.::|:||||:|.:||.:||||.|||||.|..:||..|:.|::..:.||.::|.:
Mouse   399 AKYVVSAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQINSKTKTPVIATLSSGAVAAVM 463

  Fly   384 ALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDDEDVASQ 448
            |.:|||..||:.||||||:||::|:|.|:||||:|              |...|
Mouse   464 AFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQP--------------GLCYD----------- 503

  Fly   449 SSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGR-------FEPGSV-----VSVAVMLFIFLSF 501
              ....:|..|.:|......||::.: :..|.|:       |.|.::     .|:...|..||:|
Mouse   504 --QPKYTPEKETLESCTNATLKSESQ-VTMLQGQGFSLRTLFSPSALPTRQSASLVSFLVGFLAF 565

  Fly   502 AICVELKVSWTQLY-------TGTWWALIIYGFIIFAAGTCVAVIAV---HNQNTRGLIFKVPLV 556
            .|   |.:|....|       ...|...::..|::.    |||||..   ..||.:.:.|.||.:
Mouse   566 LI---LGLSILTTYGVQAIARLEAWSLALLALFLVL----CVAVILTIWRQPQNQQKVAFMVPFL 623

  Fly   557 PFVPALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEG 604
            ||:||..|..||.|||.|.|.||:||.:|:.:|.::||.||||:|.||
Mouse   624 PFLPAFSILVNIYLMVQLSADTWIRFSIWMALGFLIYFAYGIRHSLEG 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	254/620 (41%)
Slc7a2	XP_006509313.1	2A0303	67..670	CDD:273330	258/630 (41%)