DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and slc7a10

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_002935839.2	Gene:	slc7a10 / 100494333	XenbaseID:	XB-GENE-987435	Length:	530	Species:	Xenopus tropicalis

Alignment Length:	432	Identity:	99/432 - (22%)
Similarity:	184/432 - (42%)	Gaps:	60/432 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 TKSVPTDVM---ETPLNRCLNTFDIALLG-----IGHMVGAGIYVLTGTVAKEMAGPGI-ILSFI 78
            |:.:|.|..   |:|..:.....:|.|:.     ||:::|:||::....|.:.....|: ::.::
Frog    23 TQHIPNDTTTSPESPTEKVTLKKEIGLISACAIIIGNIIGSGIFISPKGVLEHTGSVGLALIIWV 87

  Fly    79 LAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWN-ILLEHMLGAASVARAWSGY 142
            |.|.::.|.:|||||.|..:||:|..|.|.....|....|::.|: :|:.:....|.:...:|.|
Frog    88 LGGGVAALGSLCYAELGVTIPKSGGDYSYVTEIFGGLAGFLLLWSTVLIMYPTSLAVITLTFSNY 152

  Fly   143 VDSMLGGWIGNTTLELTGGIHEPGLAQYPD---------VLAFLVCIVYAAALAGGVKATAVFNS 198
            |...:                      :|:         ||:.:..::.....:..|:.......
Frog   153 VLQPV----------------------FPECIPPYDASRVLSIVCLLLLTWVNSSSVRWATRIQD 195

  Fly   199 LLTLVNIAVMVLVISVGFWYADGKNWSEAEGG------FLPYGVGGVIAGAATCFYAFVGFDSIA 257
            :.|...:..:.|:|.|||......|:.|.:..      .:| .||.:........:||.|::.:.
Frog   196 IFTAGKLLALGLIIVVGFMQIFKGNYEELKPSNAFNFWMIP-TVGQLALAFLQASFAFSGWNFLN 259

  Fly   258 TSGEEAKNPSVSIPVATVISLFVVTVGYILVSAA-LTLMIPISEINPAASLPEAFGQLNLSWAKY 321
            ...||..:|..::|.|..:|:.:||..|...:.| .|.|.| .|:..:.::...||:..|.:..:
Frog   260 YVTEEMVDPRRNLPRAIFLSIPLVTFVYTFTNIAYFTAMSP-QELMSSNAVAVTFGEKLLGYFSW 323

  Fly   322 LISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKIN--PTTQVPLLNLVVSGVMSACLA 384
            ::.:.........:.|.||...|..::.|.:|.|.|....|:  ..|.||.| ||..|. :..:.
Frog   324 IMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSLLAMIHFKYCTPVPAL-LVCCGA-TIIIM 386

  Fly   385 LVFDLAKLVEFMSIGTLLAYTIVSASVIILR------YRPME 420
            ||.|...|:.::|....|.|.:....:|:||      :||::
Frog   387 LVGDTYTLINYVSFINYLCYGVTIMGLIVLRLKKPKMFRPIK 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	96/420 (23%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
slc7a10	XP_002935839.2	2A0308	39..504	CDD:273332	94/416 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920