DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and XB985134

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_017950392.2	Gene:	XB985134 / 100492274	XenbaseID:	XB-GENE-985135	Length:	503	Species:	Xenopus tropicalis

Alignment Length:	423	Identity:	107/423 - (25%)
Similarity:	188/423 - (44%)	Gaps:	36/423 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 CTKMNRTKSVPTDVMETP---------LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPG 72
            |::...|||........|         :.:.:..|:...|.:|:|:|:||:|....|.......|
Frog     9 CSRKMHTKSKEKRANGGPGKNEPEKMQMKQEITLFNGVSLIVGNMIGSGIFVSPKGVLMYSTSFG 73

  Fly    73 I-ILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGW-NILLEHMLGAASV 135
            : ::.:.|.|..||..||||||.||.|.|:|::|.|...:.|.|.||:..| ::|:......|.:
Frog    74 LSLIIWALGGMFSMFGALCYAELGTSVIKSGASYAYILEAFGGFIAFIRLWSSLLIIEPTTQAII 138

  Fly   136 ARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVC---IVYAAALAGGVKATAVFN 197
            |..::.|:       :....|..     :|..|....:.|..:|   .:....:..|.:...||
Frog   139 AITFANYI-------VQPIFLSC-----QPPYAAVRLIAAACICTLTFINCVHVRWGTRVQDVF- 190

  Fly   198 SLLTLVNIAVMVLVISVG---FWYADGKNWSEA-EGGFLPYGVGGVIAGAATCFYAFVGFDSIAT 258
               |...|..::::||||   ....:..|.... ||.  ...:|.:.....:..|::.|:|::..
Frog   191 ---TYAKIMALIMIISVGLAKIVQGESDNLKNPFEGS--TTNIGSMALSLYSALYSYSGWDTLNF 250

  Fly   259 SGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLI 323
            ..||.|:|..::|:|..||:.|||:.|:|.:.|...::.:.::..:.::...||...|.:||:||
Frog   251 VTEEMKHPERNLPLAIAISMPVVTIIYLLTNVAYYAVLDMPDVLASDAVAVTFGNEVLGYAKWLI 315

  Fly   324 SIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFD 388
            .|.........|..|:.|..|..|..|..|.|.:....|:.....|:..|:.:|:::....||.|
Frog   316 PIAVAMSCYGGLNSSIIAASRLFYVGARQGHLPASLSLIHVENFTPVPALLFNGLIAILYLLVED 380

  Fly   389 LAKLVEFMSIGTLLAYTIVSASVIILRYRPMER 421
            :..|:.:.|....|...:..|.:|:||....:|
Frog   381 VFLLINYYSFSYWLFVGLSVAGLIVLRITQPQR 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	103/408 (25%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
XB985134	XP_017950392.2	2A0308	13..490	CDD:273332	106/419 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920