Protein Alignment CG13248 and slc7a3

DIOPT Version :10

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_012823434.1
• Gene: slc7a3 / 100144737
• XenbaseID: XB-GENE-1002485
• Length: 619
• Species: Xenopus tropicalis
• Alignment Length: 628
• Identity: 262/628 - (41%)
• Similarity: 362/628 - (57%)
• Gaps: 84/628 - (13%)

  Fly    19 KMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFI 83
            |:.|.:.:.....||...|||.|.|:..||:|..:|||:|||.|.|||:.|||.|:|.|:.|...
 Frog    13 KLLRRRVIDFGDKETGFARCLTTLDLTALGVGSTLGAGVYVLAGEVAKKSAGPSIVLCFLAAALS 77

  Fly    84 SMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLG 148
            |:||.|||||||.||||.||||:|:|:::||.|||..|||::|.::||.||||||||...|:::|
 Frog    78 SVLAGLCYAEFGARVPKTGSAYLYSYVTVGEIWAFTTGWNLILSYVLGTASVARAWSSTFDNIIG 142

  Fly   149 GWI-----GNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVM 208
            ..|     .|.:.::     |..||:|||..|.::.::..|.||.||..:|:.|.:.|.:|:.|:
 Frog   143 SHISTFFKANISFKM-----ENILAEYPDFFALILVMLLTALLAFGVSESALVNKIFTAINLLVL 202

  Fly   209 VLVISVGFWYADGKNWSEAE---------------------GGFLPYGVGGVIAGAATCFYAFVG 252
            ..||..||...|.|||:..|                     |||.|:|.|||..|||.|||||||
 Frog   203 AFVIVSGFVKGDLKNWTLTEEDYENITKELQNSTNIGSFGSGGFTPFGFGGVATGAAACFYAFVG 267

  Fly   253 FDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFGQLNLS 317
            ||.|||:|||||||..|||::.:|||.|..|.|..||||||||:|...:|..:.||:||..:...
 Frog   268 FDCIATTGEEAKNPQKSIPISIIISLLVCFVAYFGVSAALTLMMPYFLLNKDSPLPDAFKYVGWE 332

  Fly   318 WAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSGVMSAC 382
            .|:|:::||:||.::|:||||:|.:||.:||||.|||||....|:|..||.||:..:||||:||.
 Frog   333 PARYIVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFKFLAKVNKRTQTPLIATIVSGVISAI 397

  Fly   383 LALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRP--------MERIHTTIRVPAVAGSPDDDD 439
            :|.:|:|..|||.|||||||||::|:|.|.||||:|        ||::               :.
 Frog   398 MAFLFELEVLVELMSIGTLLAYSLVAACVAILRYQPDQPCSDTEMEKL---------------NG 447

  Fly   440 DDDEDVASQSSMDTSSPTSEMIE-EVLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIFLSFAI 503
            ::.|..|:.|..:.|.....::. :..|...|..             |.:|...|.|..|:...:
 Frog   448 EECEREAATSEPEKSFQMKHLLNIDCDASPSKTS-------------GHIVYGCVSLISFVFIFL 499

  Fly   504 CVELKVSWTQLYTGT--W------WALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVP 560
            |:.|......:..|:  |      .:||.:|..|        ||....:|...|.||||.:|.:|
 Frog   500 CLILAQKIDAILEGSALWISLCAILSLIAFGITI--------VIWRQPENKTRLNFKVPALPVLP 556

  Fly   561 ALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKE 603
            ...:|.|:..|:.|:|.|||||.||:.||.::||:||:|||.|
 Frog   557 LFSVFINLYFMMQLNAWTWVRFLVWMAIGFLIYFIYGVRNSVE 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	259/613 (42%)
slc7a3	XP_012823434.1	2A0303	7..599	CDD:273330	261/626 (42%)