DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and slc7a8a

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001258826.1	Gene:	slc7a8a / 100007704	ZFINID:	ZDB-GENE-121120-2	Length:	531	Species:	Danio rerio

Alignment Length:	392	Identity:	103/392 - (26%)
Similarity:	179/392 - (45%)	Gaps:	25/392 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 IGHMVGAGIYVLTGTVAKEMAGPGI-ILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISM 112
            :|:::|:||:|....|.:..:..|: ::.:||.|.|:.:.||||||.|..:||:|..|.|.....
Zfish    49 VGNIIGSGIFVSPKGVLENASSVGLALIVWILTGIITAIGALCYAELGVTIPKSGGDYSYVKDIF 113

  Fly   113 GEFWAFVIGW-NILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAF 176
            |....|:..| .:|:.:....|.:|..:|.||         ...|..|....|.||.....:...
Zfish   114 GGLAGFLRLWIAVLVIYPTNQAVIALTFSNYV---------LQPLFPTCFPPENGLRILAAICLL 169

  Fly   177 LVCIVYAAALAGGVKATAVFNS--LLTLVNIAVMVLV-ISVGFWYADGKNWSEAEGGFLP---YG 235
            |:..|..:::....:...||.:  ||.|:.|.:|.:| |..|.:|     |.|....|.|   |.
Zfish   170 LLTWVNCSSVRWATRVQDVFTAGKLLALILIIIMGIVQICKGEYY-----WLEPANAFEPFQDYD 229

  Fly   236 VGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAA-LTLMIPIS 299
            ||.:........:|:.|::.:....||..:|.|::|.|..||:.:||..|:..:.| :|.|.| .
Zfish   230 VGLIALAFLQGSFAYGGWNFLNYVTEELVDPYVNLPRAIFISIPLVTFVYVFANIAYVTAMSP-Q 293

  Fly   300 EINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINP 364
            |:..:.::...||:..|....:::.|.........:.||||...|..:|.|.:|.|.|....|:.
Zfish   294 ELLASNAVAVTFGEKLLGVMSWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSLLAMIHV 358

  Fly   365 TTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVP 429
            ....|:..|:.:.:.:..:....|:..|:.::.....|.|.:..|..|:||.:..: :|..|::.
Zfish   359 KRCTPIPALLFTCISTLLMLCTSDMYTLINYVGFINYLFYGVTVAGQIVLRIKQPD-MHRPIKIS 422

  Fly   430 AV 431
            .|
Zfish   423 LV 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	103/392 (26%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
slc7a8a	NP_001258826.1	2A0308	1..497	CDD:273332	103/392 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920