Protein Alignment CG13248 and slc7a3b

DIOPT Version :9

• Sequence 1: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_001342962.3
• Gene: slc7a3b / 100003376
• ZFINID: ZDB-GENE-120813-6
• Length: 698
• Species: Danio rerio
• Alignment Length: 646
• Identity: 259/646 - (40%)
• Similarity: 366/646 - (56%)
• Gaps: 82/646 - (12%)

  Fly    14 SGICTK---------MNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMA 69
            |.|.||         :.|.:.:....:|:...|||.|.|:..||:|..:|||:|||.|.||:|.|
Zfish    50 SSIMTKNKLASFGKMLLRRRVLDDSPVESHFARCLTTLDLIALGVGATLGAGVYVLAGEVAREKA 114

  Fly    70 GPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAAS 134
            ||.|:|||::|...|:||.|||||||.||||.||||||:|:::||.|||:.|||::|.:::|.||
Zfish   115 GPAIVLSFLIAALSSVLAGLCYAEFGARVPKTGSAYVYSYVTVGEIWAFITGWNLILSYVIGTAS 179

  Fly   135 VARAWSGYVDSMLGGWIGN-----TTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATA 194
            ||||||...||:|...|..     .:...|..:    ||:||||.|.::.::....||.||..:|
Zfish   180 VARAWSATFDSLLAQKISTFFKAFMSFPDTQNV----LAKYPDVFALILVMLLTGLLAFGVSESA 240

  Fly   195 VFNSLLTLVNIAVMVLVISVGFWYADGKNWS------------------EAE---GGFLPYGVGG 238
            :.|.:.|.:|:.|:..||..||...|..||:                  |.|   |||.|:|:.|
Zfish   241 LVNKIFTGINLVVLTFVIISGFVKGDTANWNLTVEDYINRTNITGAQKIEKEFGSGGFAPFGLNG 305

  Fly   239 VIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINP 303
            |::|||||||||||||.|||:.||||||..|||:..|.||.:....|..||||||||:|...::.
Zfish   306 VLSGAATCFYAFVGFDCIATTSEEAKNPMRSIPIGIVASLLICFFAYFGVSAALTLMMPYYMLDK 370

  Fly   304 AASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQV 368
            .:.||:||..:....|:|::|:|:||.::|:||||:|.:||.:||||.|||||....:::..|:.
Zfish   371 HSPLPQAFDYVGWGPARYIVSVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRFLSRMHKKTKT 435

  Fly   369 PLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAG 433
            |.|..:|||:::|.:|.:|||..||:.||||||||||:|:..|:||||:|..           .|
Zfish   436 PALATLVSGIVAALMAFLFDLDALVDLMSIGTLLAYTLVAVCVLILRYQPSR-----------LG 489

  Fly   434 SPDDDDDDDE----DVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRF------EP--- 485
            |...|....|    :..:...:|:....|:.:|.:             ||..||      :|
Zfish   490 SSGADVKPVELQRLEAKAVMDVDSGDEYSQDMETI-------------PLKKRFSIRMLVQPICD 541

  Fly   486 ------GSVVSVAVMLFIFLSFAICVELKVSWTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQ 544
                  |.:|..|......|...:|:.|.|...|:..|....:.:...:...:..|:.||....|
Zfish   542 VPTKISGIIVYSACGTISVLFTLLCLVLSVCLEQVAMGHPLFICLVVLLSVLSTVCIVVIWRQPQ 606

  Fly   545 NTRGLIFKVPLVPFVPALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEGE 605
            :...|.|||||:|.:|.:.||.||.||:.:...||:||.||:.||.::||.||||:|.||:
Zfish   607 SKEALTFKVPLLPILPLISIFVNIYLMMQMSGATWIRFAVWMAIGFLIYFAYGIRHSSEGK 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	252/615 (41%)
		AA_permease_C	551..601	CDD:290617	27/49 (55%)
slc7a3b	XP_001342962.3	2A0303	57..665	CDD:273330	253/635 (40%)
		AA_permease_C	613..663	CDD:290617	27/49 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750