Protein Alignment LPO and cd

DIOPT Version :9

• Sequence 1: NP_006142.1
• Gene: LPO / 4025
• HGNCID: 6678
• Length: 712
• Species: Homo sapiens
• Sequence 2: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 222/747 - (29%)
• Similarity: 359/747 - (48%)
• Gaps: 101/747 - (13%)

Human     7 LPALLASLILLQAAA----STTRAQTTRTSAISD-TVSQAKVQVNKAFLDSRTRLKTAMSSETPT 66
            ||...|:...||.||    ...:|.:....|:.| .:.:..:|.|:....|....::.  |..|.
  Fly    99 LPDEPAAEWALQQAALGHHDGAQAVSAGIKALGDREILEEGLQPNEVNTPSFRHYRSL--STNPE 161

Human    67 SRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLEVGCG----APA 127
            :|:|:              |.|.|..::...:.::.:.|.....|        .:|.|    .|.
  Fly   162 ARKLA--------------RRGYVENQATIDIAKRFNYTKQPGRS--------NIGWGPKIVLPD 204

Human   128 PVV---RCDPCSPYRTITGDCNNRRKP-ALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFP 188
            |.|   .||..:.||..||.|||::.| ..||:.....|.:..:|.||::.|      :..:...
  Fly   205 PTVLRLECDFNARYRRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAP------RVSHHGR 263

Human   189 LPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCI-- 251
            ||.||:||.||.....|   .|.|.:::...:||.:|||:   ..|.|.:|:  :.:..:.|:
  Fly   264 LPPARQVSLKIHRSSYE---TDSNFTVMLAVFGQFMDHDI---TATSLTTSQ--EGESIDCCVAA 320

Human   252 ---QGDNCFPIMFPPNDPKAGTQG-KCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSS 312
               |...|:|:...|:||...... .||.|.|:   .|.|..:...|.|:|..|:|:|||.||.:
  Fly   321 TREQHPECYPVDILPDDPYYKQYNISCMNFVRS---APAPTGRFGPRMQLNQATAFIDASVVYGN 382

Human   313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVP--CFLAGDSRASE 375
            .....::||:..:.    ::...|:|.|...||..|.....|..:..| |:.  ||.:||.||:|
  Fly   383 LEQRQNQLRSFING----SLRMFVTDDGRQLLPISSNPADGCNRVQMT-RLGKYCFESGDDRANE 442

Human   376 HILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQ- 439
            ::||.:.|.|:.|.||.|||:|:..||.|:.|:|||||||||||.:..||:.::||:|||.::.
  Fly   443 NLLLTSMHLLWARHHNYLARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISE 507

Human   440 -KWIPPYQ-------GYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWGPEPE-LPLH 494
             |.:.|.:       .|...|||.|:|.| ..||||.|..:| .:|.:..:    ...|| :.||
  Fly   508 AKGLLPAKHNLNAPDTYDPEVDPSIANCFAAAAFRFAHTLLP-GLFNISRD----NSTPEAIELH 567

Human   495 TLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHR----IHGFDLAAINT 555
            .:.||.:.:..:.|||..:  :.|..:.:|:.::..:.|:..|||:.|..    :.|.||.::|.
  Fly   568 KMLFNPFSLWAEHGIDHAL--MTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNI 630

Human   556 QRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVE 620
            ||.||||.|.|..:|..|.|....|.||::..:.:..| ..:..:|.:|.::|::.||::||.::
  Fly   631 QRGRDHGIPSYPVFRRHCRLPTVDTWEEMSQAIDNATL-DSIRQIYESPQDVDVYTGALSEPPLD 694

Human   621 RGRVGPLLACLLGKQFQQIRDGDRFWWE---NPGVFTNEQKDSLQKMSFSRLVCDN----TRITK 678
            ....||||:|::..||.:::.||..|:|   .|..||..|...:.|.|.:.::|.|    ||:.:
  Fly   695 GAIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVRE 759

Human   679 VPRDPFWANSYPYDFVDCSAID--KLDLSPWA 708
            ...........|:  |||..::  ..:..||:
  Fly   760 HVMQRLRDGGNPH--VDCQDLEGFHFNFEPWS 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LPO	NP_006142.1	An_peroxidase	138..674	CDD:281139	185/566 (33%)
		myeloperoxidase_like	283..694	CDD:188656	143/434 (33%)
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	185/566 (33%)
		peroxinectin_like	364..750	CDD:188655	137/398 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820