DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and RHO2

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_014309.3	Gene:	RHO2 / 855634	SGDID:	S000005034	Length:	192	Species:	Saccharomyces cerevisiae

Alignment Length:	207	Identity:	68/207 - (32%)
Similarity:	111/207 - (53%)	Gaps:	37/207 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWA--IDQYRIYKDVLERSWEVVDGVNV 77
            |.|::||.|.|||.|:..      .:|.:....:.|||:.  :...|            |||:.|
Yeast     9 KLVIIGDGACGKTSLLYV------FTLGKFPEQYHPTVFENYVTDCR------------VDGIKV 55

  Fly    78 SLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCK 140
            ||.||||.|  ::::.|.|:|.::|::|:.|::.:..||.|.:..|..|..|:|||.|::|||.|
Yeast    56 SLTLWDTAGQEEYERLRPFSYSKADIILIGFAVDNFESLINARTKWADEALRYCPDAPIVLVGLK 120

  Fly   141 NDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVFE 204
            .|||..       ::|.|..|       .::|..::|:.||:.:|. .|.|.|..|..||::|||
Yeast   121 KDLRQE-------AHFKENAT-------DEMVPIEDAKQVARAIGAKKYMECSALTGEGVDDVFE 171

  Fly   205 NAIRSALIARRQ 216
            .|.|::|:.:::
Yeast   172 VATRTSLLMKKE 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	67/199 (34%)
		RHO	16..211	CDD:197554	66/199 (33%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
RHO2	NP_014309.3	Rho2	7..191	CDD:206702	68/207 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900