DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and RAC10

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_201093.1	Gene:	RAC10 / 836408	AraportID:	AT5G62880	Length:	215	Species:	Arabidopsis thaliana

Alignment Length:	223	Identity:	73/223 - (32%)
Similarity:	112/223 - (50%)	Gaps:	37/223 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVN 76
            :.:|||.|||.|||||.::.....||      ..:.::|||:  |.:        .:..||:|..
plant     7 KFIKCVTVGDGAVGKTCMLICYTSNK------FPTDYIPTVF--DNF--------SANVVVEGTT 55

  Fly    77 VSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGC 139
            |:|.||||.|  |:::.|..:|..:||.:|.||:.|..|..|....|.||::.|.|.||::|||.
plant    56 VNLGLWDTAGQEDYNRLRPLSYRGADVFVLSFSLVSRASYENVFKKWIPELQHFAPGVPLVLVGT 120

  Fly   140 KNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYY-ETSVFTYFGVNEVF 203
            |.|||   .|::||:..........|          :...:.|.:|..|| |.|..|...|..||
plant   121 KLDLR---EDKHYLADHPGLSPVTTA----------QGEELRKLIGATYYIECSSKTQQNVKAVF 172

  Fly   204 ENAIRSAL--IARRQQRFWMTNLKKVQK 229
            ::||:..:  :.:::::   |..||.||
plant   173 DSAIKEVIKPLVKQKEK---TKKKKKQK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	68/200 (34%)
		RHO	16..211	CDD:197554	67/197 (34%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
RAC10	NP_201093.1	Rop_like	8..180	CDD:206705	68/200 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910