DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and ROP1

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_190698.1	Gene:	ROP1 / 824293	AraportID:	AT3G51300	Length:	197	Species:	Arabidopsis thaliana

Alignment Length:	221	Identity:	75/221 - (33%)
Similarity:	106/221 - (47%)	Gaps:	40/221 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVS 78
            ||||.|||.|||||.|:.:...|      ...:.:||||:  |.:        .:..||:|..|:
plant     7 VKCVTVGDGAVGKTCLLISYTSN------TFPTDYVPTVF--DNF--------SANVVVNGSTVN 55

  Fly    79 LRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKN 141
            |.||||.|  |:::.|..:|..:||.:|.||:.|..|..|....|.||::.:.|.||::|||.|.
plant    56 LGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENVSKKWIPELKHYAPGVPIVLVGTKL 120

  Fly   142 DLRYMYRDENYLSYFGEKGTFV--RAALKSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVF 203
            |||            .:|..|:  ..|:.......:|.|   |::|. .|.|.|..|...|..||
plant   121 DLR------------DDKQFFIDHPGAVPITTAQGEELR---KQIGAPTYIECSSKTQENVKAVF 170

  Fly   204 ENAIRSALIARRQQRFWMTNLKKVQK 229
            :.|||..|...:|::    ...|.||
plant   171 DAAIRVVLQPPKQKK----KKSKAQK 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	70/200 (35%)
		RHO	16..211	CDD:197554	68/199 (34%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
ROP1	NP_190698.1	Rop_like	6..178	CDD:206705	70/201 (35%)
ROP1	NP_190698.1	RHO	9..178	CDD:197554	68/199 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910