Protein Alignment RhoBTB and rhobtb2a

DIOPT Version :10

• Sequence 1: NP_001262107.1
• Gene: RhoBTB / 40249
• FlyBaseID: FBgn0036980
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: XP_073767321.1
• Gene: rhobtb2a / 792631
• ZFINID: ZDB-GENE-081105-67
• Length: 728
• Species: Danio rerio
• Alignment Length: 712
• Identity: 294/712 - (41%)
• Similarity: 402/712 - (56%)
• Gaps: 72/712 - (10%)

  Fly     4 MDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKD----- 63
            ||.|:|:.|.:|||:|||.||||||||||||||..::..|||:|||||||||||||:.::
Zfish    29 MDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVCLSG 93

  Fly    64 -VLERSWEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRR 127
             |||||.:|||.|:||||||||||||.|||||||||||||:||||||:|.||.:.:.||||||:.
Zfish    94 QVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVRTMWYPEIKH 158

  Fly   128 FCPDVPVILVGCKNDLRY-----MYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVA 187
            |||..|||||||:.||||     :.|....|:         |....::::.|::.|.|||||||.
Zfish   159 FCPRAPVILVGCQLDLRYADLEAVNRARRPLA---------RPIKSNEILAPEKGREVAKELGVP 214

  Fly   188 YYETSVFTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFRPPKPPPPEVTVMV-- 250
            |||||:...|||.:||:||||:|||:||..:||.::|:.||:|||||||.|||||||.:||..
Zfish   215 YYETSIVAQFGVKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIITVPAPP 279

  Fly   251 GNYRQDIYNMFLSQAYTDLVLVGAGGTKFAVHRFMLAAASSIFQRLLSTEL--TDMGGR------ 307
            .|..:....:.......|::||.....:...||..||.:||.|..|..||.  ||...|
Zfish   280 SNIEEHPSRLLEDPLCADVILVLQERQRIFAHRIYLATSSSKFYDLFLTEPRGTDETERERERPR 344

  Fly   308 ----SSSESSMVSSTFGEATIADFNDDTEALIRYESRTQRMWEHLKRRSSYQALPLMESKRSNDL 368
                |..:..|.:::|   .|.:.:||.:   |...|.......||.....:.||.: |:....:
Zfish   345 GPPLSGRDLLMRAASF---DICESSDDGD---RANLRACTSDGTLKGDGRGRLLPAL-SRAFISI 402

  Fly   369 YREL-HHPVLQSIRLVHVENHRGVNGLQTIVTLSKLISPQALHQCLRFIYTGTIDKDCDNIEEIR 432
            ..|: ..||..:.|.:            |:|.:...:.|......||::|||.:|:....:.::.
Zfish   403 QEEMVDDPVTFNPRKM------------TVVHMDPSMQPGPFRSVLRYLYTGKLDEREKELMQVA 455

  Fly   433 EAADLLELPQLTQLLSRPQTVMENSSDEPNPHICL--------RIKESMERHCIGDGCFSDVTFE 489
            ..|:|||:..|..:::.    :.|.....|..|..        |:||     |:..|.||||.|:
Zfish   456 HIAELLEVFDLRMMVAN----ILNDEAFMNQEITKAFHVRRTNRVKE-----CLAKGTFSDVVFK 511

  Fly   490 LDDGLMKAHRAVLVGRCDVMRAMLLGDFREAHSNVIVFPGVTIYTFHKLLCYLYTDQIPPISAVK 554
            ||||.:.||:.:|:..||.|.||..|.|.|:.:..::||..|......:|.||||.:......:.
Zfish   512 LDDGTIMAHKPLLISSCDWMAAMFGGPFVESCTKEVLFPNTTRSCMRAVLEYLYTGRFCSRPDLD 576

  Fly   555 CLNLLELANRLCLPRLLNLVECRVIEDLTLISQNETNETVDHCLKLLEPVKLHNAHQLAEWCMSY 619
            .:.|:.||||||||.|:.|.|...:..||..:....:...| .|..|:..:.|.||||.:||:.:
Zfish   577 AMELIVLANRLCLPHLVALTELYTVTVLTEAAMMGADIDGD-VLLYLDMAQFHCAHQLTDWCLHH 640

  Fly   620 LCVNYNLICKFSLKGLKALHQDNQEYLREHRWPPVWYLKDYDYYQRCLNELNKELKLKTSRR 681
            :|.|||.:|:...:.:||...||||:..:||||||||||:.|:|||...|..||..|...|:
Zfish   641 VCTNYNRVCRKFPRDMKAKSTDNQEHFEKHRWPPVWYLKEEDHYQRARKEREKEDYLYQKRQ 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	126/208 (61%)
		BTB1_POZ_RhoBTB	255..452	CDD:349608	47/209 (22%)
		BTB2_POZ_RhoBTB	475..582	CDD:349609	42/106 (40%)
		BACK_RHOBTB	593..669	CDD:350574	35/75 (47%)
rhobtb2a	XP_073767321.1	None