DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and Rhob

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_071987.1	Gene:	Rhob / 64373	RGDID:	621309	Length:	196	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	85/215 - (39%)
Similarity:	111/215 - (51%)	Gaps:	40/215 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSL 79
            |.|:|||.|.|||.|:..      .|..:....:||||     :..|...:|     |||..|.|
  Rat     7 KLVVVGDGACGKTCLLIV------FSKDEFPEVYVPTV-----FENYVADIE-----VDGKQVEL 55

  Fly    80 RLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKND 142
            .||||.|  |:|:.|..:|..:||:|:|||:.||.||.|....|.||::.|||:||:|||..|.|
  Rat    56 ALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD 120

  Fly   143 LRYMYRDENYLSYFGEKGTFVR---AALKSDLVMPDEARAVAKEL-GVAYYETSVFTYFGVNEVF 203
            ||   .||:           ||   |.:|.:.|..|:.||:|..: ...|.|.|..|..||.|||
  Rat   121 LR---SDEH-----------VRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVF 171

  Fly   204 ENAIRSALIARRQQRFWMTN 223
            |.|.|:||    |:|:...|
  Rat   172 ETATRAAL----QKRYGSQN 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	80/200 (40%)
		RHO	16..211	CDD:197554	79/200 (40%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
Rhob	NP_071987.1	RhoA_like	5..179	CDD:206662	80/201 (40%)
Rhob	NP_071987.1	Effector region. /evidence=ECO:0000255	34..42		4/12 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900