Protein Alignment RhoBTB and rhobtb3

DIOPT Version :10

• Sequence 1: NP_001262107.1
• Gene: RhoBTB / 40249
• FlyBaseID: FBgn0036980
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: XP_691270.6
• Gene: rhobtb3 / 562804
• ZFINID: ZDB-GENE-091204-190
• Length: 619
• Species: Danio rerio
• Alignment Length: 647
• Identity: 166/647 - (25%)
• Similarity: 256/647 - (39%)
• Gaps: 128/647 - (19%)

  Fly    57 QYRIYKD--VLER---SWEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRN 116
            |.|:..|  |:.|   ||:::|...||:             |....::|:|::.:|:...::.:.
Zfish    64 QSRVMGDVRVMVRDCPSWDILDSDWVSV-------------RSILEQADIVVIKYSVNDKLAFQQ 115

  Fly   117 CKMMWYPEIRRFCP--DVPVILVGCKNDLRYMYRDENYLSYFGEKGTFVRAALK-SDLVMPDEAR 178
            .:..:.|.:|....  .||||||.....|    .||      |...|....|.. |..|...|..
Zfish   116 VRNGYAPRLRPLLRHWGVPVILVAVGARL----NDE------GPPCTCPLCASDWSSCVPHSEGL 170

  Fly   179 AVAKELGVAYYETSVFTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFR--PPKP 241
            .::::||..|.|......|.|...|.:.:...:|...:|       |..::|..:...|  .|:|
Zfish   171 QLSRDLGATYLELPSLNNFFVGRYFGSVLEYFMIQCLKQ-------KAKERPDKRRGHRLNEPRP 228

  Fly   242 PP-------PEVTVMVGNYRQDIYNMFLSQA--YTDLVL-VGAGGTKFA-VHRFMLAAASSIFQR 295
            |.       |.|.|...::.||: ...|.:.  :.|:.. .|..|.:.. .|..:|.|.|..|::
Zfish   229 PHLDQPARLPPVRVEESSFSQDL-QWLLERGVQFADVAFYAGESGKELGWAHASVLCAVSPYFRQ 292

  Fly   296 LLSTELTDMGGRSSSESSMVSSTFGEATIADFNDDTEALIRYESRTQRMWEHLKRRSSYQALPLM 360
            ||.       ||.:.|..:     ...|..| .|...:|:       ..|:
Zfish   293 LLV-------GRQAWERPV-----SRCTCRD-RDGPHSLL-------STWD-------------- 323

  Fly   361 ESKRSNDLYRELHHPVLQSIRLVHVENHRGVNGLQTIVTLSKLISPQALHQCLRFIYTGTIDKDC 425
              ...:||.|...||          ..|     |..:|....|:. ..|.:.|.|:|.|..:
Zfish   324 --GGVDDLPRADGHP----------PGH-----LSRLVVKDPLLC-LCLWETLMFLYRGAWE--- 367

  Fly   426 DNIEEIREA-ADLLELPQ-LTQLLSRPQTVMENSS---DEPNPHICLRIKESMERHCIG----DG 481
              .|.:.|| |:.|:.|. :.||:.|.::.:....   |.|.|      :.......:|    ..
Zfish   368 --WEYLEEAIAEKLKNPMAVAQLMDRMRSFVGREKAPRDTPTP------RSQQGPMTLGSLFNSP 424

  Fly   482 CFSDVTFELDDGLMKAHRAVLVGRCDVMRAMLLGDFREAHSNVIVFPGVTIYTFHKLLCYLYTDQ 546
            .:|||.|.:...::.|||||||.|||||.||..|.:.||.|.|:...||:..||...|.|||||.
Zfish   425 LYSDVIFMVQGSVLPAHRAVLVARCDVMAAMFSGKYAEARSRVVPIHGVSSDTFLAFLEYLYTDT 489

  Fly   547 IPPISAVKCLNLLELANRLCLPRLLNLVECRVIEDLTLISQNETNETVDHCLKLLEPVKLHNAHQ 611
            ..|.|.::.:.:|..|....:.||.:|.|..|...|..:...|...|....::||...|.|||.|
Zfish   490 CCPASVLQAMAILVCAEMYQVKRLQHLCEVCVCAYLQSMPSRELASTGISVIRLLRRAKCHNADQ 554

  Fly   612 LAEWCMSYLCVNYNLICKFSLK-GLKALHQDNQEYLREHRWPPVWYLKDYDYYQRCLNELNK 672
            |..|.:.::..||.:   ||.| ....|..:.:|.:...|||...||::...||:...::.|
Zfish   555 LYVWLLHFIANNYLI---FSHKPDFLELSDEEREQVERLRWPSRGYLQELSEYQQRRRQIRK 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	38/160 (24%)
		BTB1_POZ_RhoBTB	255..452	CDD:349608	44/202 (22%)
		BTB2_POZ_RhoBTB	475..582	CDD:349609	43/110 (39%)
		BACK_RHOBTB	593..669	CDD:350574	24/76 (32%)
rhobtb3	XP_691270.6	P-loop containing Nucleoside Triphosphate Hydrolases	<80..195	CDD:476819	32/137 (23%)
		BTB_POZ	244..406	CDD:453885	45/219 (21%)
		BTB2_POZ_RHOBTB3	417..526	CDD:349669	43/108 (40%)
		BACK_RHOBTB3	536..619	CDD:350607	25/81 (31%)