DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and Rhog

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_062512.1	Gene:	Rhog / 56212	MGIID:	1928370	Length:	191	Species:	Mus musculus

Alignment Length:	201	Identity:	75/201 - (37%)
Similarity:	107/201 - (53%)	Gaps:	30/201 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVS 78
            :|||:|||.|||||.|:.....|      .....::|||:  |.|        .:...|||..|:
Mouse     4 IKCVVVGDGAVGKTCLLICYTTN------AFPKEYIPTVF--DNY--------SAQSAVDGRTVN 52

  Fly    79 LRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKN 141
            |.||||.|  ::|:.|..:|.:::|.::|||||||.|..|.:..|:||:...|||||::|||.|.
Mouse    53 LNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKK 117

  Fly   142 DLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKEL-GVAYYETSVFTYFGVNEVFEN 205
            |||   ...:.|....|:|        ...:.|.:.:|:||:: .|.|.|.|.....||.|||..
Mouse   118 DLR---AQPDTLRRLKEQG--------QAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAE 171

  Fly   206 AIRSAL 211
            |:|:.|
Mouse   172 AVRAVL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	74/198 (37%)
		RHO	16..211	CDD:197554	73/197 (37%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
Rhog	NP_062512.1	RhoG	1..191	CDD:133277	75/201 (37%)
Rhog	NP_062512.1	Effector region. /evidence=ECO:0000255	32..40		4/9 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810