DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rhoga

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001076273.1	Gene:	rhoga / 556424	ZFINID:	ZDB-GENE-060503-820	Length:	191	Species:	Danio rerio

Alignment Length:	198	Identity:	73/198 - (36%)
Similarity:	104/198 - (52%)	Gaps:	30/198 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVS 78
            :|||:|||.|||||.|:.:...|      .....:||||:  |.|        .:..:||...||
Zfish     4 IKCVVVGDGAVGKTCLLISFTTN------AFPKEYVPTVF--DNY--------SAQVLVDSKTVS 52

  Fly    79 LRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKN 141
            |.||||.|  ::|:.|..:|.::::.::|||:.||.|..|.|:.|:||:...||:||::|||.|.
Zfish    53 LNLWDTAGQEEYDRLRTLSYPQTNIFIICFSVTSPPSFENVKLKWHPEVFEHCPNVPILLVGTKK 117

  Fly   142 DLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVFEN 205
            |||   .|...|....|||..|        |...:..|:|:::.. .|.|.|..:..||.|||..
Zfish   118 DLR---DDPEELKKLKEKGLSV--------VSQQQGTALARQIHARKYMECSALSQDGVKEVFTE 171

  Fly   206 AIR 208
            |.|
Zfish   172 AAR 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	73/198 (37%)
		RHO	16..211	CDD:197554	72/196 (37%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rhoga	NP_001076273.1	P-loop_NTPase	1..191	CDD:304359	73/198 (37%)
rhoga	NP_001076273.1	RHO	6..179	CDD:197554	72/196 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810