DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rhof

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001016369.1	Gene:	rhof / 549123	XenbaseID:	XB-GENE-920536	Length:	218	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	66/231 - (28%)
Similarity:	102/231 - (44%)	Gaps:	58/231 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVS 78
            ||.|:|||...|||.|:...|           ....|..:|...:..|...:     .:...::.
Frog    26 VKIVIVGDGGCGKTSLLMVYA-----------KGSFPEQYAPSVFEKYTTTI-----TIGNKDIF 74

  Fly    79 LRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKN 141
            |.|:||.|  |:|:.|..:|...::||:|:.:.:|.|..|..:.||||:..||..||::|:|||.
Frog    75 LHLYDTAGQEDYDRLRPLSYQDVNLVLICYDVTNPTSFDNVLIKWYPEVHHFCRGVPIVLIGCKT 139

  Fly   142 DLRYMYRDENYL-----------SYF-GEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSVF 194
            |||   :|:..|           :|| ||                |..:::.   ...|.|.|..
Frog   140 DLR---KDKERLRKLRTAQQEPVTYFQGE----------------DTCKSIQ---AAEYLECSAK 182

  Fly   195 TYFGVNEVFENAIRSALIA-RRQQRFWMTNLKKVQK 229
            ....::.||:.|...||.| :|:|:     ||:.||
Frog   183 YRENIDNVFKEATLIALNAMKREQK-----LKRKQK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	57/209 (27%)
		RHO	16..211	CDD:197554	55/208 (26%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rhof	NP_001016369.1	Rho4_like	23..218	CDD:206704	66/231 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000