DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RhoBTB and rnd1a

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_998019.3	Gene:	rnd1a / 405780	ZFINID:	ZDB-GENE-040630-6	Length:	232	Species:	Danio rerio

Alignment Length:	242	Identity:	78/242 - (32%)
Similarity:	104/242 - (42%)	Gaps:	60/242 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QPHQELVKCVLVGDTAVGKTRL--ICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWE 70
            ||.....|.|||||...|||.:  :.|:.|..        .|:||||     :..|...||
Zfish     8 QPLVMRCKLVLVGDVQCGKTAMLQVLAKDCYP--------ETYVPTV-----FENYTAGLE---- 55

  Fly    71 VVDGVNVSLRLWDTFGD--HDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVP 133
             ::...|.|.||||.|.  :|..|...|..:|.|||||.|:.|.::.:....|..||..|||...
Zfish    56 -LEEQRVELSLWDTSGSPYYDNVRPLCYSDADAVLLCFDISRPDTVESSLKKWKAEIMDFCPSTR 119

  Fly   134 VILVGCKNDLR-----YMYRDENYLSYFG-EKGTFVRAALKSDLVMPDEARAVAKELGV-AYYET 191
            :||||||.|||     .|......|:... |:||.                 :||::|. .|.|.
Zfish   120 IILVGCKTDLRTDVCTLMELSNQRLTPISHEQGTL-----------------LAKQVGAEVYLEC 167

  Fly   192 SVFT-YFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFR 237
            |.|| ...::.||.:|.             :|.|.|:|.|:.|:|.|
Zfish   168 SAFTSEKSIHSVFRSAS-------------LTCLNKLQPPIKQSPTR 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	68/209 (33%)
		RHO	16..211	CDD:197554	67/206 (33%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rnd1a	NP_998019.3	P-loop_NTPase	1..232	CDD:304359	78/242 (32%)
rnd1a	NP_998019.3	RHO	16..190	CDD:197554	69/221 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900