DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rhoca

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_957444.1	Gene:	rhoca / 394125	ZFINID:	ZDB-GENE-040426-1337	Length:	193	Species:	Danio rerio

Alignment Length:	210	Identity:	84/210 - (40%)
Similarity:	108/210 - (51%)	Gaps:	36/210 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSL 79
            |.|:|||.|.|||.|:..      .|..|....:||||     :..|...:|     ||...|.|
Zfish     7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTV-----FENYIADIE-----VDSKQVEL 55

  Fly    80 RLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKND 142
            .||||.|  |:|:.|..:|..:||:|:||||.||.||.|....|.||::.|||:||:||||.|.|
Zfish    56 ALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKRD 120

  Fly   143 LRYMYRDENYLSYFGEKGTFVRAAL---KSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVF 203
            ||   .|||           .|..|   |.:.|..:|.|.:|..:.. .|.|.|..|..||.|||
Zfish   121 LR---TDEN-----------TRRELTKMKQEPVKIEEGRDMANRISAFGYLECSAKTKDGVREVF 171

  Fly   204 ENAIRSALIARRQQR 218
            |.|.|:||..|::::
Zfish   172 EMATRAALQVRKRKK 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	81/200 (41%)
		RHO	16..211	CDD:197554	80/200 (40%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rhoca	NP_957444.1	RhoA_like	5..179	CDD:206662	81/201 (40%)
rhoca	NP_957444.1	RHO	8..180	CDD:197554	81/201 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900