DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rhogd

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001349330.1	Gene:	rhogd / 393653	ZFINID:	ZDB-GENE-040426-1504	Length:	191	Species:	Danio rerio

Alignment Length:	221	Identity:	75/221 - (33%)
Similarity:	111/221 - (50%)	Gaps:	41/221 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVN 76
            :.:|||:|||.|||||.|:.:...|      .....::|||:  |.|.....        |||..
Zfish     2 QTIKCVVVGDGAVGKTCLLISYTTN------AFPEEYIPTVF--DNYSAQMS--------VDGRT 50

  Fly    77 VSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGC 139
            |||.||||.|  ::|:.|..:|.:::|.::||||.||.||.|.:..|:||:...||:||::|||.
Zfish    51 VSLNLWDTAGQEEYDRLRTLSYPQTNVFIICFSIGSPSSLANVRHKWHPEVSHHCPNVPILLVGT 115

  Fly   140 KNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMP---DEARAVAKEL-GVAYYETSVFTYFGVN 200
            |.|||   .|...:....|:|           :.|   .:...:.|:: .|.|.|.|.....||.
Zfish   116 KKDLR---SDTETIKKLKEQG-----------LAPSTQQQGGTLCKQINAVRYLECSALRQEGVR 166

  Fly   201 EVFENAIRSALIARRQQRFWMTNLKK 226
            :||.:|:|:.|....::     |.||
Zfish   167 DVFVDAVRAVLYPMTKK-----NTKK 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	71/203 (35%)
		RHO	16..211	CDD:197554	70/200 (35%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rhogd	NP_001349330.1	P-loop_NTPase	1..191	CDD:328724	75/221 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810