DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and Rac2

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	80/215 - (37%)
Similarity:	114/215 - (53%)	Gaps:	38/215 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVN 76
            :.:|||:|||.|||||.|:.:...|      .....::|||:  |.|.  .:|:      ||...
  Fly     2 QAIKCVVVGDGAVGKTCLLISYTTN------AFPGEYIPTVF--DNYS--ANVM------VDAKP 50

  Fly    77 VSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGC 139
            ::|.||||.|  |:|:.|..:|.::||.|:|||:.:|.|..|.:..|:||:|..||.||:||||.
  Fly    51 INLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGT 115

  Fly   140 KNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMP---DEARAVAKEL-GVAYYETSVFTYFGVN 200
            |.|||            .:|.|..:  ||...:.|   .:..|:|||: .|.|.|.|..|..|:.
  Fly   116 KLDLR------------DDKQTIEK--LKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLK 166

  Fly   201 EVFENAIRSAL--IARRQQR 218
            .||:.||||.|  :.|..:|
  Fly   167 TVFDEAIRSVLCPVVRGPKR 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	76/203 (37%)
		RHO	16..211	CDD:197554	76/200 (38%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	76/202 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840