DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoBTB and RHOA

DIOPT Version :9

Sequence 1:NP_001262107.1 Gene:RhoBTB / 40249 FlyBaseID:FBgn0036980 Length:783 Species:Drosophila melanogaster
Sequence 2:NP_001300870.1 Gene:RHOA / 387 HGNCID:667 Length:193 Species:Homo sapiens


Alignment Length:207 Identity:87/207 - (42%)
Similarity:111/207 - (53%) Gaps:30/207 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSL 79
            |.|:|||.|.|||.|:..      .|..|....:||||     :..|...:|     |||..|.|
Human     7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTV-----FENYVADIE-----VDGKQVEL 55

  Fly    80 RLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKND 142
            .||||.|  |:|:.|..:|..:||:|:||||.||.||.|....|.||::.|||:||:||||.|.|
Human    56 ALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120

  Fly   143 LRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGV-AYYETSVFTYFGVNEVFENA 206
            ||   .||:.....        |.:|.:.|.|:|.|.:|..:|. .|.|.|..|..||.||||.|
Human   121 LR---NDEHTRREL--------AKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMA 174

  Fly   207 IRSALIARRQQR 218
            .|:||.|||.::
Human   175 TRAALQARRGKK 186

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoBTBNP_001262107.1 RhoBTB 12..210 CDD:133275 82/197 (42%)
RHO 16..211 CDD:197554 81/197 (41%)
BTB <392..446 CDD:295341
BTB 481..575 CDD:279045
BTB 485..582 CDD:197585
RHOANP_001300870.1 RhoA_like 5..179 CDD:206662 82/198 (41%)
Effector region. /evidence=ECO:0000255 34..42 4/12 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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