DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rho4

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001018257.1	Gene:	rho4 / 3361476	PomBaseID:	SPAC16A10.04	Length:	203	Species:	Schizosaccharomyces pombe

Alignment Length:	201	Identity:	70/201 - (34%)
Similarity:	98/201 - (48%)	Gaps:	39/201 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVN--- 76
            |.|:|||...|||.|:..      .|.......:||||:  :.|         ..::..|.|
pombe    16 KLVVVGDGGCGKTCLLIV------FSSGTFPERYVPTVF--ENY---------ITDITYGPNSKV 63

  Fly    77 VSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGC 139
            :.|.||||.|  ::|:.|..:|..|:|:||||||..|.||.|....||||::.|||..|::|||.
pombe    64 IELALWDTAGQEEYDRLRPLSYPNSNVILLCFSIDCPASLNNVTEKWYPEVQHFCPRTPIVLVGL 128

  Fly   140 KNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMP---DEARAVAKELGVAYYETSVFTYFGVNE 201
            |.|||   :|.|           ....|::..:.|   .:|::||..:...|.|.|.....||||
pombe   129 KADLR---KDRN-----------ATEVLRTQGLTPVTYQQAQSVALSMNAPYVECSAKENTGVNE 179

  Fly   202 VFENAI 207
            ||:.|:
pombe   180 VFQLAV 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	70/201 (35%)
		RHO	16..211	CDD:197554	69/200 (35%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rho4	NP_001018257.1	Rho4_like	12..189	CDD:206704	70/201 (35%)
rho4	NP_001018257.1	RHO	17..185	CDD:197554	68/198 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900