DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rhogc

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_955986.1	Gene:	rhogc / 324681	ZFINID:	ZDB-GENE-030131-3402	Length:	191	Species:	Danio rerio

Alignment Length:	203	Identity:	76/203 - (37%)
Similarity:	106/203 - (52%)	Gaps:	30/203 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVN 76
            :.:|||:|||.|||||.|:.:...|      .....::|||:  |.|        .:...|||..
Zfish     2 QTIKCVVVGDGAVGKTCLLISYTTN------AFPDEYIPTVF--DNY--------STQTCVDGRA 50

  Fly    77 VSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGC 139
            |||.||||.|  ::|:.|..:|.::.|.::|||:|||.|..|.:..|:||:...||.|||:|||.
Zfish    51 VSLNLWDTAGQEEYDRLRTLSYPQTHVFIICFSVASPSSHANVRHKWHPEVCHHCPGVPVLLVGT 115

  Fly   140 KNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELG-VAYYETSVFTYFGVNEVF 203
            |.|||   .|:..|....|:|        .....|.:..|:|:.:| |.|.|.|.....||.|||
Zfish   116 KRDLR---GDKETLEKLKEQG--------MSPTTPQQGSALARSIGAVRYLECSALLQEGVREVF 169

  Fly   204 ENAIRSAL 211
            ..|:|:.|
Zfish   170 NEAVRAVL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	75/200 (38%)
		RHO	16..211	CDD:197554	74/197 (38%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rhogc	NP_955986.1	RhoG	1..191	CDD:133277	76/203 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810