DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and RhoU

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	72/207 - (34%)
Similarity:	92/207 - (44%)	Gaps:	32/207 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVV 72
            || |..:|||||||.|||||.||.:...|:      ....|:||  |.|.|....:|.|..
  Fly   388 QP-QPSIKCVLVGDGAVGKTNLILSYLENR------FNPEHIPT--ASDIYNADVNVNESP---- 439

  Fly    73 DGVNVSLRLWDTFGDHDKD--RRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVI 135
                |.|.:.||.|....|  |...|..|||.|||||:..|.:.|..|..|.|:..:  ....:|
  Fly   440 ----VHLTICDTAGQDTLDPLRELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALI 498

  Fly   136 LVGCKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSVFTYFGVN 200
            |||.:.|||......|.|...||           :.:...:|..:|..:|..|.|||..|...|.
  Fly   499 LVGTQADLRTSPNVLNKLQTNGE-----------EAISYADAWDLATTIGAKYIETSSATQDKVK 552

  Fly   201 EVFENAIRSALI 212
            :||:.||...|:
  Fly   553 DVFDTAIWEGLV 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	68/199 (34%)
		RHO	16..211	CDD:197554	67/196 (34%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	68/197 (35%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	65/192 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000