Protein Alignment RhoBTB and Rhobtb3

DIOPT Version :9

• Sequence 1: NP_001262107.1
• Gene: RhoBTB / 40249
• FlyBaseID: FBgn0036980
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_001101115.1
• Gene: Rhobtb3 / 309922
• RGDID: 1311683
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 640
• Identity: 142/640 - (22%)
• Similarity: 244/640 - (38%)
• Gaps: 158/640 - (24%)

  Fly    81 LWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVIL--VG----- 138
            :||.|.......|...|.:|::::.:::....|....|..:.|.|:|....||||:  ||
  Rat    75 VWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIKRASNSVPVIIAAVGTRQNE 139

  Fly   139 --------CKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSVFT 195
                    |.:|                         :...|...|...:|||||..|.|.....
  Rat   140 ELPCTCPLCTSD-------------------------RGSCVTTTEGIQLAKELGATYLELHSLD 179

  Fly   196 YFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPF---RPPKPPPPE----VTVMVGNY 253
            .|.:.:.|...:...:|....|:    ..:|::|..:...|   |||:...||    :.....:|
  Rat   180 DFYIGKYFGGVLEYFMIQALNQK----ASEKMKKRKMTGSFHGIRPPQLEQPEKMPVLKAEASHY 240

  Fly   254 RQDIYNMFLSQAYTDLV-----LVGAGGTKFAVHRFMLAAASSIFQRLLSTELTDMGGRSSSESS 313
            ..|:.|:.|.....|:|     ::|.    ...|:.:|.:.|.:|..|.:.:    ......:||
  Rat   241 HSDLNNLLLCCQCVDVVFYHPEVMGV----VEAHKIVLCSVSHVFMLLFNVK----SPNDIQDSS 297

  Fly   314 MVSSTFGEATIADFNDDTEALIRYESRTQRMWEHLKRRSSYQALPLMESKRSNDLYRELHHPVLQ 378
            ::.:|          .|..|:.|                 ...||....:.|:       :|.|:
  Rat   298 IIRTT----------QDLFAINR-----------------DAVLPGASQESSS-------NPPLR 328

  Fly   379 SIRLVHVENHRGVNGLQTIVTLSKLISPQALHQCLRFIYTGTIDKDCDNIEE-----IREAADLL 438
                               |.:...:....|...|||||:|..  ..:.:||     ::::.|
  Rat   329 -------------------VIVKDALFCSCLSDILRFIYSGAF--QWEELEEDVRRKLKDSGD-- 370

  Fly   439 ELPQLTQLLSRPQTVMENSSDEPNPHICLRIKESME------------RHCIGDGCFSDVTFELD 491
                ::.::.:.:.:::.    |....|||..::.:            :..:.....:||.||:.
  Rat   371 ----VSDIIEKVKCILKT----PGKINCLRNCKTYQARKPLWFYNTSLKFFLNKPMLADVVFEIQ 427

  Fly   492 DGLMKAHRAVLVGRCDVMRAMLLGDFREAHSNVIVFPGVTIYTFHKLLCYLYTDQIPPISAVKCL 556
            ...:.||||:||.||:||.||..|::.||.|.:|...||:..||...|.|||||...|....:.:
  Rat   428 GATVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETFLSFLEYLYTDSCCPAGIFQAM 492

  Fly   557 NLLELANRLCLPRLLNLVECRVIEDLTLISQNETNETVDHCLKLLEPVKLHNAHQLAEWCMSYLC 621
            .||..|....:.||.::.|..:|..|..:...|........:.||:..|.|::..|:.|.:.::.
  Rat   493 CLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIA 557

  Fly   622 VNYNLICKFSLK-GLKALHQDNQEYLREHRWPPVWYLKDYDYYQ--------RCL 667
            .||.:   ||.| ..:.|..:.:.::.:||||...|||....|:        |||
  Rat   558 TNYLI---FSQKPEFQDLSVEERSFVEKHRWPSNMYLKQLAEYRKYIHSRKCRCL 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	30/143 (21%)
		RHO	16..211	CDD:197554	30/144 (21%)
		BTB	<392..446	CDD:295341	11/58 (19%)
		BTB	481..575	CDD:279045	37/93 (40%)
		BTB	485..582	CDD:197585	39/96 (41%)
Rhobtb3	NP_001101115.1	P-loop_NTPase	34..174	CDD:304359	27/123 (22%)
		BTB	413..515	CDD:279045	38/101 (38%)
		BTB	421..518	CDD:197585	39/96 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810