Protein Alignment RhoBTB and Rhobtb2

DIOPT Version :9

• Sequence 1: NP_001262107.1
• Gene: RhoBTB / 40249
• FlyBaseID: FBgn0036980
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_001013151.1
• Gene: Rhobtb2 / 306004
• RGDID: 1309924
• Length: 728
• Species: Rattus norvegicus
• Alignment Length: 808
• Identity: 300/808 - (37%)
• Similarity: 416/808 - (51%)
• Gaps: 172/808 - (21%)

  Fly     4 MDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERS 68
            ||.|:|:.|.:|||:|||.||||||||||||||..::..|||:|||||||||||||:.::|||||
  Rat     5 MDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69

  Fly    69 WEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVP 133
            .:|||.|:||||||||||||.|||||||||||||:||||||:|.||.:.|.||||||:.|||..|
  Rat    70 RDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAP 134

  Fly   134 VILVGCKNDLRY-----MYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSV 193
            ||||||:.||||     :.|....|:         |....::::.|::.|.||||||:.||||||
  Rat   135 VILVGCQLDLRYADLEAVNRARRPLA---------RPIKPNEILPPEKGREVAKELGIPYYETSV 190

  Fly   194 FTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFRPPKPPPPEVTV---------- 248
            ...||:.:||:||||:|||:||..:||.::|:.||:|||||||.|||||||.:.|
  Rat   191 VAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEEC 255

  Fly   249 -------------------MVGNYRQDIYNMFLSQAYTDLVLV-----------GAGGTKFAVHR 283
                               .|..:...||....|..:.||.|:           |.||.:...||
  Rat   256 PAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSGPGGPRPEDHR 320

  Fly   284 -----------------FMLAAASSIFQRLLSTELTDMGGRSSSESSMVSSTFGEATIADFNDDT 331
                             |:|.|||  |.  :...:.:.||  |..:.:.:||            :
  Rat   321 SYPEQHYHHHHHHHGRDFLLRAAS--FD--VCESVDEAGG--SGPAGLRAST------------S 367

  Fly   332 EALIR-----Y---ESRTQRMWEHLKRRSSYQALPLMESKRSNDLYRELHHPVLQSIRLVHVENH 388
            :.::|     |   ..|....|.        :|...::.:.:.|       |:....||:
  Rat   368 DGILRGNGTGYLPGRGRVLSSWS--------RAFVSIQEEMAED-------PLTFKSRLM----- 412

  Fly   389 RGVNGLQTIVTLSKLISPQALHQCLRFIYTGTIDKDCDNIEEIREAADLLELPQLTQLLSRPQTV 453
                   .:|.:...|.|......|:::|||.:.::..::..|...|:|||:..|..:::.
  Rat   413 -------VVVKMDNSIQPGPFRAVLKYLYTGELGENERDLMHIAHIAELLEVFDLRMMVAN---- 466

  Fly   454 MENSSDEPNPHICL--------RIKESMERHCIGDGCFSDVTFELDDGLMKAHRAVLVGRCDVMR 510
            :.|:....|..|..        |:||     |:..|.||||||.||||.:.||:.:|:..||.|.
  Rat   467 ILNNEAFMNQEITKAFHVRRTNRVKE-----CLAKGTFSDVTFILDDGTISAHKPLLISSCDWMA 526

  Fly   511 AMLLGDFREAHSNVIVFPGVTIYTFHKLLCYLYTDQIPPISAVKCLNLLELANRLCLPRLLNLVE 575
            ||..|.|.|:.:..:|||..:......:|.||||........:..:.|:.||||||||.|:.|.|
  Rat   527 AMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIVLANRLCLPHLVALTE 591

  Fly   576 CRVIEDLTLISQNETNETVD---HCLKLLEPVKLHNAHQLAEWCMSYLCVNYNLICKFSLKGLKA 637
            ...:..|    ...|...||   ..|..||..:.|.|:|||:||:.::|.|||.:|:...:.:||
  Rat   592 QYTVTGL----MEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKA 652

  Fly   638 LHQDNQEYLREHRWPPVWYLKDYDYYQRCLNELNKE----LKLKTSRRESPSDDEGCLCFTGVFS 698
            :..:||||..:||||||||||:.|:|||...|..||    |:.:..||
  Rat   653 MSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLRRQPKRR----------------- 700

  Fly   699 CWLL--GKSKRSADVSGTTDNSNADNQI 724
             ||.  ..|..|:..:|:...|::.:.:
  Rat   701 -WLFWNSPSSPSSSAAGSASPSSSSSAV 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	126/202 (62%)
		RHO	16..211	CDD:197554	124/199 (62%)
		BTB	<392..446	CDD:295341	13/53 (25%)
		BTB	481..575	CDD:279045	41/93 (44%)
		BTB	485..582	CDD:197585	39/96 (41%)
Rhobtb2	NP_001013151.1	RhoBTB	13..207	CDD:133275	126/202 (62%)
		BTB_POZ	250..475	CDD:365784	46/273 (17%)
		BTB2_POZ_RHOBTB2	480..603	CDD:349668	47/131 (36%)
		BACK_RHOBTB2	608..704	CDD:350606	43/113 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	253	1.000	Domainoid score	I1999
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22873
Inparanoid	1	1.050	508	1.000	Inparanoid score	I1276
OMA	1	1.010	-	-		QHG49800
OrthoDB	1	1.010	-	-		D246417at33208
OrthoFinder	1	1.000	-	-		FOG0002876
OrthoInspector	1	1.000	-	-		otm45666
orthoMCL	1	0.900	-	-		OOG6_105764
Panther	1	1.100	-	-	LDO	PTHR24072
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1903
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840