DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and Rhod

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_001099793.1	Gene:	Rhod / 293660	RGDID:	1310985	Length:	210	Species:	Rattus norvegicus

Alignment Length:	221	Identity:	76/221 - (34%)
Similarity:	105/221 - (47%)	Gaps:	38/221 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EQPHQ-ELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWE 70
            |.||. ..:|.|||||...|||.|:...|      ......::.|||     :..|...|:
  Rat    10 EAPHSGRPIKVVLVGDGGCGKTSLMMVFA------NGAFPESYNPTV-----FERYNATLQ---- 59

  Fly    71 VVDGVNVSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVP 133
             :.|..|.|::|||.|  |:|:.|...|..::|:||||.:.:|.|..|....||||:..||..||
  Rat    60 -MKGKPVRLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVP 123

  Fly   134 VILVGCKNDLRYMYRDENYLSYFGEKG----TFVRAALKSDLVMPDEARAVAKELGVAYYETSVF 194
            :|:||||.|||   :|:..::...:|.    |:.|.        .|.||:|.   .|||.|.|..
  Rat   124 IIVVGCKIDLR---KDKVLVNTLRKKRLEPVTYHRG--------HDMARSVG---AVAYLECSAR 174

  Fly   195 TYFGVNEVFENAIRSALIARRQQRFW 220
            .:..|..||:.|...|| :.|...||
  Rat   175 LHDNVEAVFQEAAEVAL-SSRSHNFW 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	68/203 (33%)
		RHO	16..211	CDD:197554	67/200 (34%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
Rhod	NP_001099793.1	Rho4_like	16..210	CDD:206704	73/215 (34%)
Rhod	NP_001099793.1	RHO	20..192	CDD:197554	69/202 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900