DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoBTB and rho2

DIOPT Version :9

Sequence 1:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_594569.1	Gene:	rho2 / 2542773	PomBaseID:	SPAC16.01	Length:	200	Species:	Schizosaccharomyces pombe

Alignment Length:	224	Identity:	75/224 - (33%)
Similarity:	105/224 - (46%)	Gaps:	52/224 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWA--IDQYRIYKDVLE 66
            |...||.:.  |.|:|||.|.|||.|:..      .:|....:.:||||:.  :...|
pombe     1 MLQSQPIRR--KLVVVGDGACGKTSLLSV------FTLGYFPTEYVPTVFENYVSDCR------- 50

  Fly    67 RSWEVVDGVNVSLRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFC 129
                 |||.:|.|.||||.|  ::::.|..:|.::.::|:.|:|.||.||.|....|..||...|
pombe    51 -----VDGKSVQLALWDTAGQEEYERLRPMSYAKAHIILVGFAIDSPDSLENVSTKWIEEINTLC 110

  Fly   130 PDVPVILVGCKNDLR--------YMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGV 186
            |:||.||||.|.|||        ...|::|:                   |...:|..||:.:|.
pombe   111 PNVPFILVGMKADLRSDPVAIEEMRRRNQNF-------------------VKSQQAELVAQRIGA 156

  Fly   187 -AYYETSVFTYFGVNEVFENAIRSALIAR 214
             .|.|.|..|..||::|||.|.|:||..|
pombe   157 RKYMECSSLTGDGVDDVFEAATRAALTVR 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	69/210 (33%)
		RHO	16..211	CDD:197554	68/207 (33%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
rho2	NP_594569.1	Rho2	8..199	CDD:206702	72/217 (33%)
rho2	NP_594569.1	RHO	11..183	CDD:197554	69/208 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810